Kodi mankhwala a khansa ya prostate angagwiritsidwe ntchito bwanji?
Pali njira zingapo zochiritsira khansa ya prostate, malinga ndi mlingo ndi kuopsa kwa khansa, komanso thanzi la wodwalayo ndi zokonda zake.
Njira zina zofala zochiritsira zimaphatikizapo:
1. Kuyang'anira mwakhama: Njira imeneyi imaphatikizapo kuyang'anitsitsa khansa ndi kufufuza ndi kuyesa nthaŵi ndi nthaŵi, m'malo moyamba kulandira chithandizo nthaŵi yomweyo.
Ikhoza kukhala yoyenera kwa amuna omwe ali ndi khansa ya prostate ya chiopsezo chochepa.
2. Opaleshoni: Opaleshoni yochotsa prostate ndi opaleshoni yochotsa prostate gland.
Ikhoza kuchitidwa mwa opaleshoni yotseguka kapena laparoscopically (pogwiritsa ntchito zilonda zing'onozing'ono ndi zida zapadera).
3. Mankhwala a ma radiation: Mankhwalawa amagwiritsa ntchito ma radiation amphamvu kwambiri kuti aphe maselo a khansa.
Itha kuperekedwa kunja (kuchokera ku makina kunja kwa thupi) kapena mkati (kudzera m'ma implants omwe amaikidwa pafupi ndi chotupa).
4. Mankhwala a mahomoni: Mankhwalawa amachepetsa kuchuluka kwa mahomoni achimuna (androgens) m'thupi, amene angalepheretse kapena kuletsa kukula kwa khansa ya prostate.
Ikhoza kugwiritsidwa ntchito yokha kapena yogwirizanitsidwa ndi mankhwala ena.
5. Chemotherapy: Mankhwalawa amagwiritsa ntchito mankhwala opha maselo a khansa.
Ikhoza kugwiritsidwa ntchito pa khansa ya prostate yopita patsogolo imene yafalikira ku mbali zina za thupi.
6. Immunotherapy: Mankhwala ameneŵa amathandiza chitetezo cha m'thupi kulimbana ndi khansa.
Ikhoza kugwiritsidwa ntchito kwa khansa ya prostate yopita patsogolo yomwe sinayankhe ku mankhwala ena.
7. Mankhwala opangidwa ndi anthu: Mankhwalawa amapangidwa ndi majini kapena mapuloteni enaake amene amathandiza maselo a khansa kukula ndi kupulumuka.
Ikhoza kugwiritsidwa ntchito kwa khansa ya prostate yopita patsogolo yomwe sinayankhe ku mankhwala ena.
8. Cryotherapy: Mankhwalawa amagwiritsa ntchito kuzizira kwambiri kuti aziziziritsa ndi kupha maselo a khansa.
Ikhoza kugwiritsidwa ntchito pa khansa ya prostate yoyambirira kapena ya khansa yomwe yabwereranso pambuyo pa mankhwala ena.
9. High-intensity focused ultrasound (HIFU): Mankhwalawa amagwiritsa ntchito mafunde a phokoso a pafupipafupi kuti atenthe ndi kuwononga maselo a khansa.
Ikhoza kugwiritsidwa ntchito pa khansa ya prostate yoyambirira kapena ya khansa yomwe yabwereranso pambuyo pa mankhwala ena.
10. Kudikira mosamala: Njira imeneyi imaphatikizapo kuyang'anitsitsa khansa ndi kufufuza ndi kuyesa nthaŵi ndi nthaŵi, koma osayamba mankhwala pokhapokha ngati zizindikiro zayamba kuonekera kapena kusintha.
Ikhoza kukhala yoyenera kwa amuna achikulire omwe ali ndi khansa ya prostate yomwe imakula pang'onopang'ono ndi matenda ena oopsa.
Nkofunika kukambitsirana njira zonse zochiritsira ndi gulu la chisamaliro chaumoyo kuti mudziŵe njira yabwino kwambiri yochitira zinthu pa nkhani iliyonse.
Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.
Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.
Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.
Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.
Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.
de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.
Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.
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Chonde titumizireni imelo ndi funso / lingaliro lililonse.
How to treat prostate cancer?
There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.
Some common treatments include:
1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.
It may be suitable for men with low-risk prostate cancer.
2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.
It can be done through open surgery or laparoscopically (using small incisions and specialized tools).
3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.
It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).
4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.
It can be used alone or in combination with other treatments.
5. Chemotherapy: This treatment uses drugs to kill cancer cells.
It may be used for advanced prostate cancer that has spread to other parts of the body.
6. Immunotherapy: This treatment helps the immune system fight cancer.
It may be used for advanced prostate cancer that has not responded to other treatments.
7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.
It may be used for advanced prostate cancer that has not responded to other treatments.
8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.
It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.
It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.
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