Say pathophysiology na lung cancer et ontutukoy ed saray pananguman ed normal a proseso tan mekanismo na laman ya nagagawa sano ontubo tan onloor so lung cancer.
Say kanser ed bala et komplikadon sakit ya resulta na agnakontrol ya ibaleg tan panlalaok na saray selula ed bala.
Sarayan selula so nayarin mamawala na tumor tan onkayat ed arum a parte na laman, a manresulta ed nanduruman sintomas tan komplikasyon.
Say pathophysiology na lung cancer et nalalanor so pigaran sengegan, kaiba lay genetic mutations, kaliberliber, tan kabibilay.
Nayarin wala ray mutation ed DNA na selula na bala, kanian agla nakontrol so ibaleg tan panlalaok na selula.
Sarayan mutation so nayarin natawir odino naala, tan nayarin pansengegan iratan na pakaka-ekspo ed saray carcinogen, a singa say asewek na tabako, radon, asbestos, tan polusyon ed dagem.
Say lung cancer et nayarin ikategorya ed duaran klase: small cell lung cancer (SCLC) tan non-small cell lung cancer (NSCLC).
Nayarin nanduruma so pathophysiology na sarayan klase na kanser ed bala, lapud nanduruma so genetic mutation da tan nanduruma so reaksion da ed panagtambal.
Say pathophysiology na kanser ed bala et nalalanor met so pantutulongan na saray selula na kanser tan saray tissue ed kaliberliber, kaiba lay immune system.
Saray selula na kanser et agnakontrol na immune system kanian ontubo tan onkayat iratan.
Niarum ni, say tumor microenvironment et nayarin mamaaligwas ed ibubulaslas tan metastasis na tumor diad pangiter na marakep a kaliberliber parad saray selula na kanser.
Say pathophysiology na lung cancer et komplikado tan mabilabilay, tan tuloytuloy a panseseetan na saray researcher ya aralen iray manunan paraan pian napaaligwas so panagtambal tan say pansumpalan na pasyente.
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Nurwidya F, Syahruddin E, Yunus F: Pain management in lung cancer. Adv Respir Med. 2016, 84 (6): 331-336.
Khan KA, Kennedy MP, Moore E, Crush L, Prendeville S, Maher MM, Burke L, Henry MT: Radiological characteristics, histological features and clinical outcomes of lung cancer patients with coexistent idiopathic pulmonary fibrosis. Lung. 2015, 193 (1): 71-7.
Paramanantham A, Asfiya R, Das S, McCully G, Srivastava A: Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. Int J Mol Sci. 2022, 23 (21): .
Lee D, Kim Y, Chung C: Scientific Validation and Clinical Application of Lung Cancer Organoids. Cells. 2021, 10 (11): .
Mucchietto V, Crespi A, Fasoli F, Clementi F, Gotti C: Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment. Curr Pharm Des. 2016, 22 (14): 2160-9.
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What is pathophysiology of lung cancer?
The pathophysiology of lung cancer refers to the changes in the normal physiological processes and mechanisms that occur in the development and progression of lung cancer.
Lung cancer is a complex disease that arises from the uncontrolled growth and division of abnormal cells in the lungs.
These cells can form tumors and spread to other parts of the body, leading to various symptoms and complications.
The pathophysiology of lung cancer involves several factors, including genetic mutations, environmental factors, and lifestyle choices.
Genetic mutations can occur in the DNA of lung cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can be caused by exposure to carcinogens, such as tobacco smoke, radon, asbestos, and air pollution.
Lung cancer can be classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is further divided into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.
The pathophysiology of these types of lung cancer can differ, as they have different genetic mutations and respond differently to treatment.
The pathophysiology of lung cancer also involves the interaction between cancer cells and the surrounding tissue, including the immune system.
Cancer cells can evade the immune system, allowing them to grow and spread unchecked.
Additionally, the tumor microenvironment can promote tumor growth and metastasis by providing a supportive environment for cancer cells.
The pathophysiology of lung cancer is a complex and dynamic process, and researchers are continuously working to better understand the underlying mechanisms to develop more effective treatments and improve patient outcomes.
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