Kansarka qanjirka 'prostate' wuxuu inta badan ku dhacaa ragga da'da ah, iyadoo kiisaska badankood ay ku dhacaan ragga da'doodu ka weyn tahay 65.
Intaas waxaa sii dheer, ragga leh taariikhda qoyska ee kansarka qanjirka 'prostate' waxay halis badan ku jiraan, sida ragga Afrikaanka-Mareykanka ah iyo ragga ka soo jeeda Kariibiyaanka.
Cudurka kansarka qanjirka 'prostate' wuxuu ku lug leeyahay koritaanka aan la xakamayn karin iyo kala qaybsanaanta unugyada qanjirka 'prostate'.
Tani waxay dhici kartaa sababtoo ah isbeddellada hiddo-wadaha ee keena muujinta xad-dhaafka ah ee arrimaha koritaanka qaarkood ama joojinta hiddo-wadaha xakameynta burooyinka.
Isbedeladaasi waxay keeni karaan koritaanka unugyada oo aan la xakamayn karin, taasoo keeni karta in uu soo baxo burooyin.
Marka uu burku koro, wuxuu ku faafi karaa unugyada iyo xubnaha u dhow, sida qanjirka dhiigga, qanjirka dhiigga, iyo unugyada lymph ee u dhow.
Xaaladaha qaarkood, unugyada kansarka waxay ka soo bixi karaan burooyinka aasaasiga ah waxayna ku faafi karaan qaybaha kale ee jirka iyagoo maraya dhiigga ama nidaamka lymphatic, geedi socod loo yaqaan metastasis.
Marka uu kansarku faafo, way adkaan kartaa in la daweeyo.
Kansarka qanjirka 'prostate' waxaa sidoo kale saameyn ku yeelan kara waxyaabo hormoon ah, gaar ahaan hormoonka 'androgen' ee 'testosterone'.
Testosterone wuxuu kicin karaa koritaanka unugyada kansarka qanjirka 'prostate', daaweyn badan oo loogu talagalay kansarka qanjirka 'prostate' waxay ujeedadoodu tahay in la yareeyo heerarka hormoonkan ama la xakameeyo saameyntiisa.
Marka la soo koobo, cudurka kansarka qanjirka 'prostate' wuxuu ku lug leeyahay koritaanka aan la xakamayn karin iyo kala qaybsanaanta unugyada qanjirka 'prostate', oo ay saameyn ku yeelan karaan hiddo-wadaha, hormoonada, iyo arrimaha deegaanka.
Fahamka hababka aasaasiga ah ee cudurka ayaa muhiim u ah horumarinta daaweyn wax ku ool ah iyo hagaajinta natiijooyinka bukaanada qaba kansarka qanjirka 'prostate'.
Zobniw CM, Causebrook A, Fong MK: Clinical use of abiraterone in the treatment of metastatic castration-resistant prostate cancer. Res Rep Urol. 2014, 6 (): 97-105.
Lim HY, Agarwal AM, Agarwal N, Ward JH: Recurrent epistaxis as a presenting sign of androgen-sensitive metastatic prostate cancer. Singapore Med J. 2009, 50 (5): e178-80.
Kohli M, Qin R, Jimenez R, Dehm SM: Biomarker-based targeting of the androgen-androgen receptor axis in advanced prostate cancer. Adv Urol. 2012, 2012 (): 781459.
Nelson JB, Hedican SP, George DJ, Reddi AH, Piantadosi S, Eisenberger MA, Simons JW: Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med. 1995, 1 (9): 944-9.
Msaouel P, Nandikolla G, Pneumaticos SG, Koutsilieris M: Bone microenvironment-targeted manipulations for the treatment of osteoblastic metastasis in castration-resistant prostate cancer. Expert Opin Investig Drugs. 2013, 22 (11): 1385-400.
Kotani K, Sekine Y, Ishikawa S, Ikpot IZ, Suzuki K, Remaley AT: High-density lipoprotein and prostate cancer: an overview. J Epidemiol. 2013, 23 (5): 313-9.
Jadvar H: Molecular imaging of prostate cancer: a concise synopsis. Mol Imaging. , 8 (2): 56-64.
Diidmada masuuliyada: caafimaadka
Boggan waxaa loogu talagalay ujeedooyin waxbarasho iyo macluumaad oo keliya mana aha bixinta talo caafimaad ama adeegyo xirfadeed.
Macluumaadka la bixiyo waa in aan loo isticmaalin in lagu ogaado ama lagu daweeyo dhibaato caafimaad ama cudur, kuwa raadinaya talo caafimaad oo shaqsiyeed waa inay la tashadaan dhakhtar ruqsad haysta.
Fadlan la soco in shabakada neerfaha ee soo saarta jawaabaha su'aalaha, ay tahay mid aan sax ahayn marka ay timaado waxyaabaha tirooyinka ah. Tusaale ahaan, tirada dadka la ogaaday inay qabaan cudur gaar ah.
Had iyo jeer raadi talada dhakhtarkaaga ama daryeel caafimaad oo kale oo u qalma oo ku saabsan xaalad caafimaad. Waligaa ha iska indho tirin talada caafimaadka xirfadeed ama ha dib u dhigin raadinta sababtoo ah wax aad ka akhrisay boggan internetka. Haddii aad u maleyneyso inaad leedahay xaalad caafimaad oo degdeg ah, wac 911 ama u tag qolka gurmadka degdegga ah ee kuugu dhow isla markiiba. Xiriirka dhakhtarka iyo bukaanka looma abuuro boggan internetka ama isticmaalkiisa. BioMedLib ama shaqaalaheeda, ama qof kasta oo ka qaybqaata boggan internetka, ma sameeyaan wax matalaad ah, si cad ama si macquul ah, oo ku saabsan macluumaadka halkan lagu bixiyo ama isticmaalkiisa.
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Ogeysiisyada waa in lagu diraa qoraal ahaan emayl (eeg qaybta "Contact" ee cinwaanka emaylka).
DMCA waxay u baahan tahay in ogeysiiskaaga ku saabsan xadgudubka xuquuqda daabacaadda ee la sheegay uu ku jiro macluumaadka soo socda: (1) sharaxaadda shaqada xuquuqda daabacaadda ee ay ku saabsan tahay xadgudubka la sheegay; (2) sharaxaadda nuxurka xadgudubka la sheegay iyo macluumaadka ku filan ee noo oggolaanaya inaan helno nuxurka; (3) macluumaadkaaga xiriirka adiga, oo ay ku jiraan cinwaankaaga, lambarka taleefanka iyo cinwaanka emaylkaaga; (4) bayaan aad ku leedahay aaminaad wanaagsan oo ah in nuxurka habka lagu cabiray uusan oggolaan milkiilaha xuquuqda daabacaadda, ama wakiilkiisa, ama hawlgalka sharci kasta;
(5) bayaan aad saxiixday oo aad ku cadeyneyso in macluumaadka ku jira ogeysiiska uu sax yahay iyo in aad awood u leedahay in aad dhaqan geliso xuquuqda daabacaadda ee la sheeganayo in la jabiyay;
iyo (6) saxiix jireed ama elektaroonig ah oo ka yimid milkiilaha xuquuqda daabacaadda ama qof loo oggol yahay inuu ku dhaqmo magaca milkiilaha xuquuqda daabacaadda.
Haddii aadan ku darin dhammaan macluumaadka kor ku xusan waxay keeni kartaa dib u dhac ku yimaada ka baaraandegista cabashadaada.
Xiriirka
Fadlan noogu soo dir emayl su'aal kasta / soo jeedin.
What is pathophysiology of prostate cancer?
The pathophysiology of prostate cancer refers to the underlying mechanisms and processes that lead to the development and progression of the disease.
Prostate cancer is a malignant tumor that arises from the cells of the prostate gland, which is a small, walnut-shaped organ located below the bladder in men.
The prostate gland produces seminal fluid, which nourishes and transports sperm.
The exact cause of prostate cancer is not fully understood, but several factors are known to increase the risk of developing the disease.
These include age, family history, race, and certain genetic mutations.
Prostate cancer is more common in older men, with the majority of cases occurring in men over the age of 65.
Additionally, men with a family history of prostate cancer are at an increased risk, as are African American men and men of Caribbean descent.
The pathophysiology of prostate cancer involves the uncontrolled growth and division of cells within the prostate gland.
This can occur due to genetic mutations that lead to the overexpression of certain growth factors or the inactivation of tumor suppressor genes.
These mutations can result in the unregulated growth of cells, leading to the formation of a tumor.
As the tumor grows, it can invade nearby tissues and organs, such as the bladder, rectum, and nearby lymph nodes.
In some cases, cancer cells can break away from the primary tumor and spread to other parts of the body through the bloodstream or lymphatic system, a process known as metastasis.
Once the cancer has spread, it can be more difficult to treat.
Prostate cancer can also be influenced by hormonal factors, particularly the androgen hormone testosterone.
Testosterone can stimulate the growth of prostate cancer cells, and many treatments for prostate cancer aim to reduce the levels of this hormone or block its effects.
In summary, the pathophysiology of prostate cancer involves the uncontrolled growth and division of cells within the prostate gland, which can be influenced by genetic, hormonal, and environmental factors.
Understanding the underlying mechanisms of the disease is crucial for developing effective treatments and improving outcomes for patients with prostate cancer.
Disclaimer: medical
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Qiyaastii
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Waxaan ka bilownay 35 milyan oo daabacaadyo caafimaad oo ku saabsan PubMed/Medline. Sidoo kale, bogagga RefinedWeb.
Eeg "Tixraacyada" sidoo kale "Qeexitaanka mas'uuliyadda".
