How to treat Prostate cancer?

['Iscurtade custa pàgina']

Comente curare su tumore a sa prostata?

Ddoi iant vàrias optzionis de tratamentu po su cancru de sa prostata, a segunda de su stùdiu e de sa gravidadi de su cancru, aici comenti de sa saludi generali e de is preferéntzias personalis de su malàdiu.

Carchi tratamentu cumunu includet:

1. Sorvegliàntzia ativa: Custu acostamentu ìmplicat su controllu astrintu de su tumore cun controllos e esames regulares, imbetzes de cumintzare deretu su tratamentu.

Podet èssere adatadu a òmines cun cancru de sa prostata a arriscu bassu.

2. Chirurgia: Una prostatectomia est una protzedura chirùgica pro bogare sa ghiandula prostàtica.

Si podet fàghere pro mèdiu de un'interventu abertu o laparoscòpicu (usende incisiones minores e istrumentos ispetzializados).

3. Radioterapia: custu tratamentu usat radiatziones a arta energia pro ochìere sas tzèllulas tumorales.

Podet èssere donadu in forma esterna (dae una màchina foras de su corpus) o interna (pro mèdiu de impiantos postos acanta de su tumore).

4. Terapia ormonale: Custu tratamentu mènguat sos livellos de ormones maschiles (andrògenos) in su corpus, chi podent rallentare o firmare sa crèschida de su tumore a sa prostata.

Si podet impreare a sa sola o in cumbinatzione cun àteros tratamentos.

5. Cimioterapia: Custu tratamentu usat meighinas pro ochìere sas tzèllulas tumorales.

Podet èssere impreadu pro su tumore a sa prostata avantzadu chi si nch'est ispartu a àteras partes de su corpus.

6. Immunoterapia: custu tratamentu agiudat su sistema immunitàriu a cumbàtere su cancru.

Podet èssere impreadu pro su tumore a sa prostata avantzadu chi non at rispostu a àteros tratamentos.

7. Teràpia mirada: Custa terapia tirat a genes o proteinas ispetzìficos chi agiudant sas tzèllulas tumorales a crèschere e subravìvere.

Podet èssere impreadu pro su tumore a sa prostata avantzadu chi non at rispostu a àteros tratamentos.

8. Crioterapia: Custu tratamentu usat su fritu estremu pro congelare e ochìere sas tzèllulas tumorales.

Podet èssere impreadu pro su tumore a sa prostata in fase primidia o pro su tumore chi est torradu a nàschere a pustis de àteros tratamentos.

9. Ultra-sonu focalizadu a arta intensidade (HIFU): Custu tratamentu usat undas sonoras a frecuèntzia arta pro caentare e distruire sas tzèllulas tumorales.

Podet èssere impreadu pro su tumore a sa prostata in fase primidia o pro su tumore chi est torradu a nàschere a pustis de àteros tratamentos.

10. Aspettada attenta: Custu acostamentu ìmplicat de sighire de acanta su tumore cun controllos e esames regulares, ma no cumintzare su tratamentu a mancu chi is sìntomos si mustrant o càmbiant.

Podet èssere adatadu a òmines antzianos cun tumore a sa prostata a crèschida lenta e àteras cunditziones sanitàrias graves.

Est de importu a discùtere totu sas optziones de tratamentu cun un'iscuadra sanitària pro determinare sa mègius manera de agire pro ogni casu individuale.

['Referèntzias']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

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How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

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