What are the risk factors for Breast cancer?

['Lalela lelikhasi']

Ngutiphi tintfo letingabangela kutsi ube nemdlavuza wemabele?

Kunetintfo letinyenti letibangela umdlavuza wemabele, letinye tato tingashintjwa kantsi letinye tingashintjwa.

Nati letinye tintfo letibangela kutsi ube sengotini:

1. Budzala: Ingoti yekutsi umuntfu abe nemdlavuza wemabele iyakhula njengobe achubeka akhula, futsi linyenti lalabo labanemdlavuza licala kubasikati labangetulu kweminyaka lengu-50.

2. Umlandvo wemndeni: Kuba nesihlobo lesisedvute lesinesifo semdlavuza wemabele, njengamake, dzadze nobe indvodzakati, kungakhulisa ematfuba ekutsi ube naso.

3. Kushintja kwetitfo temtimba letakheka kubantfu: Kushintja kwetitfo temtimba letakheka kubantfu, njengekutsi BRCA1 naBRCA2, kungenta umuntfu abe sengotini yekungenwa ngumdlavuza wemabele.

4. Umlandvo wekutala: Kucala ngekushesha kuya esikhatsini, kuphela ngekushesha kwekuhamba kwesikhatsi, kungabi nebantfwana nobe kuba nebantfwana ngemuva kweminyaka lengu-30 kungakhulisa ingoti.

5. Kwelashwa ngemahomoni: Kusebentisa ema-hormone lahlanganisa i-estrogen ne-progesterone sikhatsi lesidze ngemuva kwekuphela kwesikhatsi sekuya esikhatsini kungakhulisa ingoti.

6. Kunatsa tjwala: Kunatsa tjwala kungakhulisa ematfuba ekungenwa ngumdlavuza wemabele.

7. Kukhuluphala: Kuba nesisindvo lesengetiwe nobe kukhuluphala kakhulu kungakhulisa ingoti yekungenwa ngulesifo, ikakhulukati ngemuva kwekuphela kwesikhatsi sekuya esikhatsini.

8. Kutivocavoca: Kwehluleka kutivocavoca kungakhulisa ingoti yekutsi ube nesifo semsheko.

9. Kuba sengotini yekushiswa ngemisebe: Kuba sengotini yekushiswa ngemisebe kakhulu, ikakhulukati ebuntfwaneni, kungakhulisa ingoti.

10. Emabele lacinile: Besifazane labanemabele lacinile basengotini lenkhulu yekungenwa ngumdlavuza wemabele.

11. Kuba netinyanga: Besifazane labacala kuba netinyanga basebancane (basengakabi neminyaka lengu-12 budzala) nobe labacala kuba netinyanga sekudlule sikhatsi (basengakabi neminyaka lengu-55 budzala) basengotini lenkhulu.

12. Kumunyisa: Besifazane labangakaze bamunyise bantfwana babo banematfuba lamanyenti ekungenwa ngumdlavuza wemabele.

Kubalulekile kwati kutsi kuba netintfo letiyingoti letitsite akusho kutsi umuntfu nakanjani utawuba nemdlavuza wemabele, kantsi futsi kungabi netintfo letiyingoti akusho kutsi umuntfu angeke abe nawo umdlavuza wemabele.

Nobe kunjalo, kucondza letizatfu tekugula kungasita bantfu kutsi bente tincumo letikahle mayelana nemphilo yabo futsi kunciphise bungoti.

['Tintfo letibhalwe phansi']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wung SF, Hepworth JT, Sparenga D, Merkle CJ: Cardiovascular Disease Risk and Breast Cancer Outcomes: A Pilot Study. Oncol Nurs Forum. 2015, 42 (5): E330-8.

Frankl G: Risk factors in breast cancer: are they important, are they the same in pre- and post-menopausal breast cancer patients? Oncology. 1980, 37 (1): 41-5.

Ho PJ, Lau HSH, Ho WK, Wong FY, Yang Q, Tan KW, Tan MH, Chay WY, Chia KS, Hartman M, Li J: Incidence of breast cancer attributable to breast density, modifiable and non-modifiable breast cancer risk factors in Singapore. Sci Rep. 2020, 10 (1): 503.

Barnard ME, Boeke CE, Tamimi RM: Established breast cancer risk factors and risk of intrinsic tumor subtypes. Biochim Biophys Acta. 2015, 1856 (1): 73-85.

Hines LM, Risendal B, Slattery ML, Baumgartner KB, Giuliano AR, Sweeney C, Rollison DE, Byers T: Comparative analysis of breast cancer risk factors among Hispanic and non-Hispanic white women. Cancer. 2010, 116 (13): 3215-23.

Rosner B, Glynn RJ, Eliassen AH, Hankinson SE, Tamimi RM, Chen WY, Holmes MD, Mu Y, Peng C, Colditz GA, Willett WC, Tworoger SS: A Multi-State Survival Model for Time to Breast Cancer Mortality among a Cohort of Initially Disease-Free Women. Cancer Epidemiol Biomarkers Prev. 2022, 31 (8): 1582-1592.

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['(5) sitatimende sakho, lesisayinwe ngaphasi kwesijeziso sekufunga emanga, sekutsi umniningwane lokuso satiso ucinisile nekutsi uneligunya lekuvikela emalungelo e-copyright lasolwa kutsi ephuliwe;']

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['Kwehluleka kufaka yonkhe lemininingwane lengenhla kungaholela ekubambelekeni kwekusetjentwa kwesikhalo sakho.']

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What are the risk factors for breast cancer?

There are several risk factors for breast cancer, some of which are modifiable and others that are not.

Here are some of the most common risk factors:

1. Age: The risk of developing breast cancer increases with age, with most cases occurring in women over the age of 50.

2. Family history: Having a close relative, such as a mother, sister, or daughter, with breast cancer increases your risk.

3. Genetic mutations: Certain inherited gene mutations, such as BRCA1 and BRCA2, increase the risk of developing breast cancer.

4. Reproductive history: Early menarche (start of menstruation), late menopause, and having no children or having the first child after age 30 can increase the risk.

5. Hormone replacement therapy: Long-term use of combined estrogen and progesterone hormone therapy after menopause can increase the risk.

6. Alcohol consumption: Drinking alcohol increases the risk of breast cancer.

7. Obesity: Being overweight or obese increases the risk, especially after menopause.

8. Physical activity: Lack of physical activity can increase the risk.

9. Radiation exposure: Exposure to high doses of radiation, particularly during childhood, can increase the risk.

10. Breast density: Women with dense breasts have a higher risk of developing breast cancer.

11. Menstrual history: Women who started menstruating early (before age 12) or went through menopause late (after age 55) have a slightly higher risk.

12. Breastfeeding: Women who have never breastfed have a slightly higher risk of developing breast cancer.

It is important to note that having one or more risk factors does not mean that a person will definitely develop breast cancer, and not having any risk factors does not guarantee that a person will not develop breast cancer.

However, understanding these risk factors can help individuals make informed decisions about their health and potentially reduce their risk.

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