What causes Breast cancer?

['Lalela lelikhasi']

Yini lebangela umdlavuza wemabele?

Kute intfo yinye lebangela umdlavuza wemabele, kodvwa tintfo letinyenti tingakhulisa bungoti bekutfola lesifo.

Letinye taletizatfu tifaka ekhatsi:

1. Budzala: Ingoti yekutsi umuntfu lomsikati abe nemdlavuza wemabele iyakhula njengobe achubeka akhula.

2. Umlandvo wemndeni: Umfati usengotini lenkhulu yekungenwa ngumdlavuza wemabele nangabe kunesihlobo sakhe (make, dzadze nobe indvodzakati) lesike saba nawo.

3. Kushintja kwetitfo temtimba letakheka kubantfu: Kushintja kwetitfo temtimba letakheka kubantfu, njengekutsi BRCA1 naBRCA2, kungenta umuntfu abe sengotini yekungenwa ngumdlavuza wemabele.

4. Umlandvo wekutala: Kucala kuya esikhatsini usemncane, kuphela kwesikhatsi sekuya esikhatsini sekwephuta, kungabi nebantfwana nobe kuba nebantfwana ngemuva kweminyaka lengu-30 kungakhulisa ingoti yekutsi ube nemdlavuza wemabele.

5. Kwelashwa ngemakhemikhali lafaka ekhatsi ema-hormone: Besifazane labasebentisa imitsi yekwelapha bantfu labaphelelwe sikhatsi, basengotini lenkhulu yekungenwa ngumdlavuza wemabele.

6. Kunatsa tjwala: Kunatsa tjwala kungakhulisa ematfuba ekungenwa ngumdlavuza wemabele.

7. Kukhuluphala: Kuba nesisindvo lesengetiwe nobe kukhuluphala kakhulu kungakhulisa ematfuba ekungenwa ngumdlavuza wemabele.

8. Kungenami umtimba: Kuphila imphilo yekungaphumuli kungakhulisa ematfuba ekungenwa ngumdlavuza wemabele.

9. Kuba sengotini yemisebe: Kuba sengotini yemisebe lematima, ikakhulukati ebuntfwaneni, kungakhulisa ematfuba ekutsi ube nemdlavuza wemabele.

10. Emabele lacinile: Besifazane labanemabele lacinile basengotini lenkhulu yekungenwa ngumdlavuza wemabele.

11. Umlandvo wekuya esikhatsini: Besifazane labacala kuya esikhatsini kusenesikhatsi nobe labacala sekwephutile kuba khona kwabo, basengotini lenkhulu yekungenwa ngumdlavuza wemabele.

12. Kumunyisa: Besifazane labangakaze bamunyise bantfwana babo banematfuba lamanyenti ekungenwa ngumdlavuza wemabele.

13. Kuvimbela Kutalwa: Besifazane labasebentisa emaphilisi ekuvimbela kutalwa basengotini lenkhulu yekungenwa ngumdlavuza wemabele.

Kubalulekile kwati kutsi kuba nayinye nobe ngetulu yaletintfo letiyingoti akusho kutsi umuntfu lomsikati nakanjani utawuba nemdlavuza wemabele, kantsi futsi bomake labanyenti lababa nemdlavuza wemabele bete tintfo letatiwako letiyingoti.

Ngetulu kwaloko, letinye tintfo letibangela kugula, njengeminyaka kanye nemlandvo wemndeni, angeke tishintjwe, kantsi letinye, njengendlela yekuphila, tingashintjwa kute kuncishiswe ingoti.

['Tintfo letibhalwe phansi']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Yoneda T: Cellular and molecular basis of preferential metastasis of breast cancer to bone. J Orthop Sci. 2000, 5 (1): 75-81.

Demirci S, Eser E, Ozsaran Z, Tankisi D, Aras AB, Ozaydemir G, Anacak Y: Validation of the Turkish versions of EORTC QLQ-C30 and BR23 modules in breast cancer patients. Asian Pac J Cancer Prev. 2011, 12 (5): 1283-7.

Kluttig A, Schmidt-Pokrzywniak A: Established and Suspected Risk Factors in Breast Cancer Aetiology. Breast Care (Basel). , 4 (2): 82-87.

Tabar L, Duffy SW, Yen MF, Warwick J, Vitak B, Chen HH, Smith RA: All-cause mortality among breast cancer patients in a screening trial: support for breast cancer mortality as an end point. J Med Screen. 2002, 9 (4): 159-62.

Gonzalez P, Lim JW, Wang-Letzkus M, Flores KF, Allen KM, Castañeda SF, Talavera GA: Breast Cancer Cause Beliefs: Chinese, Korean, and Mexican American Breast Cancer Survivors. West J Nurs Res. 2015, 37 (8): 1081-99.

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['Ngaso sonkhe sikhatsi cela seluleko kudokotela wakho nobe lomunye loniketa lusito lwetemphilo mayelana nesimo sakho sekugula. Ungalokotsi unganaki seluleko sebucwepheshe nobe wephute kusitfola ngenca yalokutsite lokufundze kulewebhusayithi. Uma ucabanga kutsi kungenteka unekugula, shayela 911 nobe uye egunjini lelisedvute lekuphutfuma ngekushesha. Kute budlelwane emkhatsini wetekwelapha nesigulane lobentiwa ngulewebhusayithi nobe kusetjentiswa kwayo. I-BioMedLib nobe basebenti bayo, nobe ngumuphi umuntfu lofaka sandla kulewebhusayithi, akenti nobe nguyiphi imiculu, lechazako nobe lechazako, mayelana nemniningwane loniketwe lapha nobe kusetjentiswa kwayo.']

['Liciniso: copyright']

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['Nangabe ukholelwa kutsi nobe nguyiphi intfo nobe intfo lekhona kulewebhusayithi nobe etinhlelweni tetfu yephula emalungelo akho, wena (nobe ummeli wakho) ungasitfumelela satiso ucele kutsi leyo nto nobe intfo isuswe nobe ivinjelwe.']

['Tatiso kumele titfunyelwe nge-email (buka likheli le-email kusigaba "Sekuchumana").']

['I-DMCA idzinga kutsi satiso sakho sekuhlukumeta emalungelo eluntfu sicukatse lemininingwane lelandzelako: (1) inchazelo yemsebenti logunyatwe emalungelo eluntfu lokutsiwa uphasiwe; (2) inchazelo yalokucuketfwe lokutsiwa kuphasiwe kanye nemininingwane leyenele kutsi sikhone kutfola lokucuketfwe; (3) imininingwane yekutsintsana nawe, kufaka ekhatsi likheli lakho, inombolo yelucingo nelikheli le-email; (4) sitatimende sakho sekutsi unenkolelo lenhle yekutsi lokucuketfwe ngendlela lokhonjiwe akukavumeleki kumnikati wemalungelo eluntfu, nobe kummeli wakhe, nobe ngekusebenta kwanoma ngumuphi umtsetfo; ']

['(5) sitatimende sakho, lesisayinwe ngaphasi kwesijeziso sekufunga emanga, sekutsi umniningwane lokuso satiso ucinisile nekutsi uneligunya lekuvikela emalungelo e-copyright lasolwa kutsi ephuliwe;']

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['Kwehluleka kufaka yonkhe lemininingwane lengenhla kungaholela ekubambelekeni kwekusetjentwa kwesikhalo sakho.']

['Kuchumana']

['Sicela usitfumelele i-email nganobe nguwuphi umbuto / umbono.']

What causes breast cancer?

There is no single cause of breast cancer, but several factors can increase the risk of developing the disease.

Some of these factors include:

1. Age: The risk of breast cancer increases as a woman gets older.

2. Family history: A woman's risk of breast cancer is higher if she has a close relative (mother, sister, or daughter) who has had breast cancer.

3. Genetic mutations: Certain inherited gene mutations, such as BRCA1 and BRCA2, increase the risk of breast cancer.

4. Reproductive history: Early menstruation, late menopause, and having no children or having the first child after age 30 can increase the risk of breast cancer.

5. Hormone replacement therapy: Women who take hormone replacement therapy for menopause have a higher risk of breast cancer.

6. Alcohol consumption: Drinking alcohol increases the risk of breast cancer.

7. Obesity: Being overweight or obese increases the risk of breast cancer.

8. Physical inactivity: A sedentary lifestyle can increase the risk of breast cancer.

9. Radiation exposure: Exposure to high doses of radiation, particularly during childhood, can increase the risk of breast cancer.

10. Breast density: Women with dense breasts have a higher risk of breast cancer.

11. Menstrual history: Women who started menstruating early or went through menopause late have a slightly higher risk of breast cancer.

12. Breastfeeding: Women who have never breastfed have a slightly higher risk of breast cancer.

13. Birth control: Women who use oral contraceptives have a slightly higher risk of breast cancer.

It is important to note that having one or more of these risk factors does not mean that a woman will definitely develop breast cancer, and many women who develop breast cancer have no known risk factors.

Additionally, some risk factors, such as age and family history, cannot be changed, while others, such as lifestyle factors, can be modified to reduce the risk.

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