Ugonjwa wa Alzheimer ni ugonjwa unaoendelea wa neva ambao hasa huathiri ubongo, ukisababisha kupoteza kumbukumbu, kupungua kwa utambuzi, na mabadiliko ya tabia.
Sababu halisi ya ugonjwa wa Alzheimer's haijulikani kikamili, lakini inaaminika kwamba husababishwa na chembe za urithi, mazingira, na mtindo-maisha.
Baadhi ya mambo yanayoweza kusababisha ugonjwa wa Alzheimer's ni pamoja na:
1. Urithi: Jeni fulani zimegunduliwa ambazo huongeza hatari ya kupatwa na ugonjwa wa Alzheimer, hasa jeni la apolipoprotein E (APOE).
2. Umri: Hatari ya kupatwa na ugonjwa wa Alzheimer's huongezeka kadiri mtu anavyozeeka, na watu wengi hugunduliwa kuwa na ugonjwa huo baada ya umri wa miaka 65.
3. Historia ya familia: Kuwa na historia ya familia ya ugonjwa wa Alzheimer kunaweza kuongeza hatari ya kupata ugonjwa huo.
4. Majeraha ya kichwa: Historia ya majeraha ya kichwa, hasa yale yanayosababisha kupoteza fahamu, yaweza kuongeza hatari ya ugonjwa wa Alzheimer.
5. Sababu za hatari za moyo na mishipa ya damu: Hali kama vile shinikizo la damu la juu, kiwango cha juu cha kolesteroli, na kisukari zaweza kuongeza hatari ya kupatwa na ugonjwa wa Alzheimer.
6. Mambo yanayohusiana na mtindo wa maisha: Mtindo wa maisha usio na shughuli nyingi, lishe mbaya, na ukosefu wa kichocheo cha kiakili waweza kuongeza hatari ya ugonjwa wa Alzheimer.
7. Uchochezi: Uchochezi sugu katika ubongo waweza kuchangia maendeleo ya ugonjwa wa Alzheimer.
8. Mkazo wa oksidi: Ukosefu wa usawaziko kati ya uzalishaji wa radicals huru na uwezo wa mwili wa kuondoa sumu hizo waweza kuchangia maendeleo ya ugonjwa wa Alzheimer.
9. Mabamba ya amyloid na mitego ya neurofibrillary: Mkusanyiko wa mabamba ya amyloid na mitego ya neurofibrillary katika ubongo ni alama ya ugonjwa wa Alzheimer, lakini jukumu wanalofanya katika maendeleo ya hali hiyo halieleweki kikamili.
Ni muhimu kutambua kwamba kisababishi cha ugonjwa wa Alzheimer ni tata na yaelekea kinahusisha mambo hayo yote pamoja.
Utafiti unaendelea ili kuelewa vizuri zaidi utaratibu unaoongoza na kutengeneza matibabu yenye matokeo kwa ajili ya hali hiyo yenye kuharibu.
Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.
Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.
Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.
Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.
Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.
Kanusho la dhima: matibabu
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Utoaji wa dhima: hakimiliki
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Kama unaamini kwa imani nzuri kwamba maudhui yoyote au nyenzo zilizotolewa kuhusiana na tovuti yetu au huduma inakiuka hakimiliki yako, wewe (au wakala wako) unaweza kutuma sisi taarifa kuomba kwamba maudhui au nyenzo kuondolewa, au upatikanaji wake kuzuiwa.
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(5) taarifa na wewe, saini chini ya adhabu ya ushahidi wa uongo, kwamba habari katika taarifa ni sahihi na kwamba una mamlaka ya kutekeleza haki za hakimiliki ambayo ni madai ya kukiuka;
na (6) saini ya kimwili au ya elektroniki ya mmiliki wa hakimiliki au mtu aliyeidhinishwa kutenda kwa niaba ya mmiliki wa hakimiliki.
Kushindwa kujumuisha habari zote hapo juu kunaweza kusababisha ucheleweshaji wa usindikaji wa malalamiko yako.
Mawasiliano
Tafadhali tutumie barua pepe na swali lolote / pendekezo.
What causes alzheimer?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.
The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.
Some of the factors that may contribute to the development of Alzheimer's disease include:
1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.
2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.
4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.
5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.
6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.
7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.
8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.
9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.
It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.
Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.
Disclaimer: medical
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Disclaimer: copyright
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Karibu
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Tunaanza na machapisho milioni 35 ya biomedical ya PubMed/Medline. Pia, kurasa za wavuti za RefinedWeb.
