Bolwetse jwa Alzheimer ke bolwetse jo bo etegelang pele jwa go koafala ga boboko jo bo amang boboko thata, bo dira gore motho a se ka a tlhola a gakologelwa dilo, a se ka a kgona go akanya sentle le go fetola tsela e a itshwarang ka yone.
Ga go itsiwe sentle gore tota ke eng se se bakang bolwetse jwa Alzheimer, mme go dumelwa gore bo bakwa ke dilo tse di amanang le dijini, tikologo le tsela e motho a tshelang ka yone.
Mangwe a mabaka a a ka nnang a dira gore motho a nne le bolwetse jwa Alzheimer ke ano:
1. Dijini: Go ile ga lemogiwa dijini dingwe tse di ka dirang gore motho a nne le bolwetse jwa Alzheimer, segolobogolo jini ya apolipoprotein E (APOE).
2. Dingwaga: Kotsi ya go tshwarwa ke bolwetse jwa Alzheimer e oketsega fa motho a ntse a gola, mme bontsi jwa batho ba bo lemogiwa fa ba setse ba na le dingwaga di le 65.
3. Malwetse a lelapa: Go nna le lelapa le le nang le bolwetse jwa Alzheimer go ka oketsa kotsi ya gore motho a nne le jone.
4. Go gobala mo tlhogong: Go gobala mo tlhogong mo go kileng ga direga, segolobogolo mo go felelang ka gore motho a idibale, go ka oketsa kotsi ya gore motho a nne le bolwetse jwa Alzheimer.
5. Dilo tse di ka bakang bolwetse jwa pelo: Maemo a a jaaka kgatelelo e e kwa godimo ya madi, kholeseterole e e kwa godimo le bolwetse jwa sukiri a ka oketsa kotsi ya go tshwarwa ke bolwetse jwa Alzheimer.
6. Dilo tse di amanang le tsela e motho a tshelang ka yone: Go nna fela o sa dire sepe, go sa je dijo tse di nang le dikotla le go sa dirise tlhaloganyo sentle go ka dira gore motho a nne mo kotsing ya go tshwarwa ke bolwetse jwa Alzheimer.
7. Go ruruga: Go ruruga go go sa foleng ga boboko go ka dira gore motho a nne le bolwetse jwa Alzheimer.
8. Go ngomoga pelo ka ntlha ya okosejene: Go sa lekalekane ga selekanyo se dikhemikale tse di kotsi di ntshiwang ka sone le bokgoni jwa mmele jwa go di ntsha botlhole go ka dira gore motho a nne le bolwetse jwa Alzheimer.
9. Amyloid plaques le neurofibrillary tangles: Go koelana ga plaques tsa amyloid le neurofibrillary tangles mo bobokong ke letshwao la bolwetse jwa Alzheimer, mme seabe se di nang le sone mo go direng gore bolwetse jono bo nne teng ga se tlhaloganngwe ka botlalo.
Go botlhokwa go ela tlhoko gore se se bakang bolwetse jwa Alzheimer se raraane mme go ka direga gore se bakwa ke dilo tseno tsotlhe.
Go sa ntse go dirwa dipatlisiso go tlhaloganya botoka gore bolwetse jono bo bakwa ke eng le go dira kalafi e e ka bo alafang.
Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.
Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.
Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.
Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.
Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.
['Go se ikarabele: kalafi']
['Web site eno e diretswe go ruta le go naya tshedimosetso fela mme ga e neye kgakololo ya kalafi kgotsa ditirelo tsa seporofešenale.']
['Tshedimosetso e e neelwang ga e a tshwanela go dirisiwa go bona bolwetse kana go alafa bothata jwa botsogo, mme batho ba ba batlang kgakololo ya kalafi ba tshwanetse go ikgolaganya le ngaka e e nang le laesense.']
['Tsweetswee ela tlhoko gore thulaganyo ya methapo e e dirang dikarabo tsa dipotso tseno, ga e a tlhomama fa go tla mo dilong tsa dipalo. Ka sekai, palo ya batho ba ba nang le bolwetse bongwe jo bo rileng.']
['Ka metlha batla kgakololo ya ngaka ya gago kgotsa moabi yo mongwe wa kalafi yo o tshwanelegang malebana le boemo jwa kalafi. Le ka motlha o se ka wa itlhokomolosa kgakololo ya kalafi ya porofeshenale kgotsa wa diega go e batla ka ntlha ya sengwe se o se badileng mo website eno. Fa o akanya gore o ka tswa o na le boemo jwa tshoganyetso jwa kalafi, leletsa 911 kgotsa o ye kwa kamoreng ya tshoganyetso e e gaufi le wena ka bonako. Ga go na kamano epe ya ngaka le molwetse e e tlisiwang ke website eno kgotsa go e dirisa. BioMedLib kgotsa badiri ba yone, kgotsa ope fela yo o tsentseng letsogo mo website eno, ga ba dire ditshupetso dipe, tse di tlhamaletseng kgotsa tse di sa tlhamalalang, malebana le tshedimosetso e e mo go yone kgotsa go e dirisa.']
['Go ikgatholosa: ditshwanelo tsa bokwadi']
['Molao wa Digital Millennium Copyright wa 1998, 17 U.S.C. § 512 (the DMCA) o tlamela ka kgetse ya beng ba ditshwanelo ba ba dumelang gore matheriale o o tlhagelelang mo inthaneteng o gataka ditshwanelo tsa bona go ya ka molao wa ditshwanelo wa U.S.']
['Fa o dumela ka pelo yotlhe gore tshedimosetso kgotsa matheriale o o mo website ya rona kgotsa ditirelo tsa rona o gataka ditshwanelo tsa gago tsa semolao, wena (kgotsa moemedi wa gago) o ka re romelela kitsiso o kopa gore tshedimosetso eo kgotsa matheriale oo o tlosiwe kgotsa o thibelwe go o fitlhelela.']
['Dikitsiso di tshwanetse go romelwa ka go kwala ka imeili (leba karolo ya "Contact" go bona aterese ya imeili).']
['DMCA e batla gore kitsiso ya gago ya go tlolwa ga ditshwanelo tsa gago e akaretse tshedimosetso e e latelang: (1) tlhaloso ya tiro e e sireleditsweng ka ditshwanelo e go tweng e tlotswe; (2) tlhaloso ya diteng tse go tweng di tlotswe le tshedimosetso e e lekaneng go re letla go bona diteng; (3) tshedimosetso ya go ikgolaganya le wena, go akaretsa aterese ya gago, nomoro ya mogala le aterese ya imeile; (4) polelo ya gago ya gore o dumela ka pelo yotlhe gore diteng tse di tlotsweng ga di a letlelelwa ke mong wa ditshwanelo tsa gago, kgotsa moemedi wa gagwe, kgotsa ka molao ope; ']
['(5) polelo e e saenilweng ke wena, e e supang gore tshedimosetso e e mo kitsisong e boammaaruri le gore o na le thata ya go diragatsa ditshwanelo tsa botaki tse go tweng di gatakilwe;']
['le (6) saena ya mmatota kgotsa ya eleketeroniki ya mong wa tshwanelo ya go gatisa kgotsa motho yo o filweng tetla ya go dira mo boemong jwa mong wa tshwanelo ya go gatisa. ']
['Fa o sa akaretse tshedimosetso yotlhe e e fa godimo e ka nna ya diegisa go sekasekwa ga ngongorego ya gago.']
['Go Ikgolaganya']
['Tsweetswee re romelele imeile ka potso/kgakololo epe fela.']
What causes alzheimer?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.
The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.
Some of the factors that may contribute to the development of Alzheimer's disease include:
1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.
2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.
4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.
5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.
6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.
7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.
8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.
9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.
It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.
Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.
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['Mo e ka nnang']
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['Re simolola ka dikgatiso di le dimilione di le 35 tsa tsa kalafi ya ditshedi tsa PubMed/Medline. Gape, ditsebe tsa Web tsa RefinedWeb.']
