What are the risk factors for Alzheimer?

Zintoni ezibangela ukuba umntu abe nesifo i-Alzheimer?

Zininzi izinto ezinokubangela isifo i-Alzheimer, eziquka:

1. Ubudala: Umngcipheko wokuba nesi sifo uyanda njengoko umntu ekhula, yaye abantu abaninzi bafumanisa ukuba banaso emva kweminyaka engama-65 ubudala.

2. I-Genetics: Ukuba kwintsapho yakho kukho umntu onesifo sika-Alzheimer okanye unezifo ezithile, njenge-APOE-e4, kunokukwenza ube sesichengeni ngakumbi.

3. Ukwenzakala entloko: Ukuba umntu wakha wonzakala kakhulu entloko okanye wakha wabanjwa kaninzi kusenokumenza abe sesichengeni sokuba nesifo sika-Alzheimer.

4. Impilo yentliziyo nemithambo-luvo: Iimeko ezichaphazela intliziyo nemithambo-luvo, ezinjengoxinezeleko lwegazi, icholesterol eninzi, isifo seswekile nokutyeba ngokugqithiseleyo, zinokubangela ukuba umntu abe nesifo seAlzheimer.

5. Indlela yokuphila: Ukutshaya, ukusela ngokugqithiseleyo nokungawenzi umthambo kunokubangela ukuba umntu abe nesi sifo.

6. Ukungasebenzi kakuhle kwengqondo: Ukungaphangeli kakuhle kwengqondo nokungafundi ngokwaneleyo kunokubangela ukuba umntu abe nesifo seAlzheimer.

7. Ukuphazamiseka kokulala: Ukuphazamiseka kokulala, njengokuphefumla xa ulele, kunokukwenza ube sesichengeni sokuba nesifo sika-Alzheimer.

8. Izinto ezichaphazela ingqondo: Ukudandatheka, uxinezeleko nokuzahlula kwabanye kunokubangela ukuba umntu abe nesifo seAlzheimer.

Kubalulekile ukuqaphela ukuba ukuba nomnye okanye ngaphezulu kwezi zinto zenza ukuba umntu abe sesichengeni akuthethi ukuba umntu uza kuba nesifo sika-Alzheimer, kwaye abanye abantu abangenazo ezi zinto zenza ukuba umntu abe sesichengeni basenokuba naso esi sifo.

Noko ke, ukuqonda ezi zinto zinokubangela ukuba umntu abe sesichengeni kunokumnceda athabathe amanyathelo okuwanciphisa aze abe nengqondo esempilweni.

['Iimbekiselo']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

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['Izaziso kufuneka zithunyelwe ngokubhaliweyo nge-imeyile (jonga kwicandelo elithi "Qhagamshelana" ukuze ufumane idilesi ye-imeyile).']

['I-DMCA ifuna ukuba isaziso sakho sokutyholwa ngokophula ilungelo lokushicilela siquke ezi nkcukacha zilandelayo: (1) inkcazelo yomsebenzi onelungelo lokushicilela ongundaba-mlonyeni wokutyholwa ngokophula; (2) inkcazelo yomxholo otyholwa ngokophula kunye nolwazi olwaneleyo ukusivumela ukuba sifumane umxholo; (3) iinkcukacha zokuqhagamshelana nawe, kuquka idilesi yakho, inombolo yomnxeba nedilesi ye-imeyile; (4) ingxelo yakho yokuba unokholo olulungileyo lokuba umxholo ngendlela ekhalazwa ngayo awugunyaziswanga ngumnini welungelo lokushicilela, okanye iarhente yakhe, okanye ngokusebenza kwawo nawuphi na umthetho; ']

['(5) ingxelo yakho, esayinwe phantsi kwesohlwayo sobuxoki, yokuba ulwazi olukwisibhengezo luchanekile kwaye unegunya lokunyanzelisa amalungelo okushicilela ekuthiwa aphulwe;']

['kwaye (6) utyikityo lomzimba okanye lwe-elektroniki lomnini welungelo lokushicilela okanye lomntu ogunyazisiweyo ukuba enze egameni lomnini welungelo lokushicilela. ']

['Ukungabandakanyi lonke ulwazi olungentla kungakhokelela ekulibaziseni ukuphathwa kwesikhalazo sakho.']

['Unxibelelwano']

['Nceda usithumelele i-imeyile ngayo nayiphi na imibuzo / iingcebiso.']

What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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