What are the risk factors for Breast cancer?

['Phulaphula eli phepha']

Ziziphi izinto ezinokubangela umhlaza wamabele?

Zininzi izinto ezinokubangela umhlaza wamabele, ezinye zazo zinokulungiswa ezinye azinakulungiswa.

Nazi ezinye zezona zinto ziqhelekileyo ezibangela ukuba umntu abe sesichengeni:

1. Ubudala: Umngcipheko wokuba nomhlaza wamabele uyanda njengoko umntu ekhula, yaye ubukhulu becala ubonakala kumabhinqa angaphezu kweminyaka engama-50 ubudala.

2. Imbali yentsapho: Ukuba nesalamane esisondeleyo, njengomama, udade okanye intombi, enomhlaza wamabele kwandisa amathuba okuba ube nawo.

3. Ukutshintsha kwemizila yemfuza: Ukutshintsha kwemizila yemfuza ethile, njengeBRCA1 neBRCA2, kwandisa amathuba okuba nomhlaza wamabele.

4. Imbali yokuzala: Ukuqala kokuya exesheni ngaphambi kwexesha, ukuyeka ukuya exesheni emva kwexesha, ukungabi nabantwana okanye ukuba nomntwana wokuqala emva kweminyaka engama-30 ubudala kunokuyandisa ingozi.

5. Unyango oluthabathel' indawo iihomoni: Ukusetyenziswa kwexesha elide konyango oluthabathel' indawo iihomoni oludibanisa i-estrogen neprogesterone emva kokuyeka ukuya exesheni kunokulandisa ingozi.

6. Ukusetyenziswa kotywala: Ukusetyenziswa kotywala kwandisa amathuba okuba nomhlaza wamabele.

7. Ukutyeba ngokugqithiseleyo: Ukutyeba ngokugqithiseleyo okanye ukutyeba ngokugqithiseleyo kwandisa umngcipheko, ingakumbi emva kokuyeka ukuya exesheni.

8. Ukwenza umthambo: Ukungawenzi umthambo kunokuyenza ibe yingozi ngakumbi.

9. Ukuchanabeka kwimitha: Ukuchanabeka kwimitha emikhulu, ngokukodwa xa usengumntwana, kunokuyandisa ingozi.

10. Ubunzima bamabele: Amabhinqa anamabele amakhulu asengozini enkulu yokuba nomhlaza wamabele.

11. Ukuya exesheni: Amabhinqa aqala ukuya exesheni ngaphambi kwexesha (ngaphambi kweminyaka eli - 12) okanye aphelelwa exesheni emva kwexesha (emva kweminyaka engama - 55) asengozini engakumbi.

12. Ukuncancisa: Amabhinqa angazange ancancise anamathuba aphakamileyo okuhlaselwa ngumhlaza wamabele.

Kubalulekile ukuqaphela ukuba ukuba nomnye okanye ngaphezulu wemiba yomngcipheko akuthethi ukuba umntu uza kuba nomhlaza wamabele, kwaye ukungabi nayo nayiphi na imiba yomngcipheko akuthethi ukuba umntu akayi kuba nomhlaza wamabele.

Noko ke, ukuqonda ezi zinto zinokubangela ingozi kunokunceda abantu benze izigqibo ezifanelekileyo ngempilo yabo baze banciphise ingozi.

['Iimbekiselo']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wung SF, Hepworth JT, Sparenga D, Merkle CJ: Cardiovascular Disease Risk and Breast Cancer Outcomes: A Pilot Study. Oncol Nurs Forum. 2015, 42 (5): E330-8.

Frankl G: Risk factors in breast cancer: are they important, are they the same in pre- and post-menopausal breast cancer patients? Oncology. 1980, 37 (1): 41-5.

Ho PJ, Lau HSH, Ho WK, Wong FY, Yang Q, Tan KW, Tan MH, Chay WY, Chia KS, Hartman M, Li J: Incidence of breast cancer attributable to breast density, modifiable and non-modifiable breast cancer risk factors in Singapore. Sci Rep. 2020, 10 (1): 503.

Barnard ME, Boeke CE, Tamimi RM: Established breast cancer risk factors and risk of intrinsic tumor subtypes. Biochim Biophys Acta. 2015, 1856 (1): 73-85.

Hines LM, Risendal B, Slattery ML, Baumgartner KB, Giuliano AR, Sweeney C, Rollison DE, Byers T: Comparative analysis of breast cancer risk factors among Hispanic and non-Hispanic white women. Cancer. 2010, 116 (13): 3215-23.

Rosner B, Glynn RJ, Eliassen AH, Hankinson SE, Tamimi RM, Chen WY, Holmes MD, Mu Y, Peng C, Colditz GA, Willett WC, Tworoger SS: A Multi-State Survival Model for Time to Breast Cancer Mortality among a Cohort of Initially Disease-Free Women. Cancer Epidemiol Biomarkers Prev. 2022, 31 (8): 1582-1592.

['Ukuzikhusela: unyango']

['Le webhsayithi yenzelwe ukufundisa nokunika inkcazelo kuphela yaye ayibonisi ukuba inikela amacebiso ezonyango okanye iinkonzo zobungcali.']

['Inkcazelo enikelweyo ayifanele isetyenziselwe ukuxilonga okanye ukunyanga ingxaki yempilo okanye isifo, yaye abo bafuna icebiso lonyango lobuqu bafanele babonane nogqirha onelayisensi.']

['Nceda uqaphele ukuba inethiwekhi ye-neural eyenza iimpendulo kwimibuzo, ayichanekanga xa kufikwa kumxholo wenani. Umzekelo, inani labantu abafunyaniswe benesifo esithile.']

['Soloko ucela icebiso kugqirha wakho okanye komnye umboneleli wezempilo ofanelekileyo malunga nemeko yakho yezonyango. Ungaze ungayihoyi ingcebiso yezonyango okanye ulibazise ukufuna ngenxa yento oyifunde kule webhusayithi. Ukuba ucinga ukuba unengxaki yezonyango, tsalela umnxeba ku-911 okanye uye kwigumbi likaxakeka elikufutshane ngoko nangoko. Akukho buhlobo bukagqirha nomguli obudalwa yile webhusayithi okanye ukusetyenziswa kwayo. I-BioMedLib okanye abasebenzi bayo, okanye nabani na onegalelo kule webhusayithi, abenzi zimelo, ngokucacileyo okanye ngokungangqalanga, ngokubhekisele kulwazi olunikezwe apha okanye ekusetyenzisweni kwalo.']

['Ukuzikhulula: ilungelo lokushicilela']

['Umthetho we-Digital Millennium Copyright ka-1998, 17 U.S.C. § 512 (i-DMCA) ubonelela ngeendlela zokubhena kubanini bamalungelo obunini abakholelwa ukuba izinto ezibonakala kwi-Intanethi ziphula amalungelo abo phantsi komthetho welungelo lokushicilela wase-US. ']

['Ukuba ukholelwa ukuba kukho umxholo okanye izinto ezenziwe zafumaneka kwi-website yethu okanye iinkonzo eziphula ilungelo lakho lokushicilela, wena (okanye iarhente yakho) ungathumela isaziso esicela ukuba umxholo okanye izinto zisuswe, okanye ukufikelela kuzo kuvalwe. ']

['Izaziso kufuneka zithunyelwe ngokubhaliweyo nge-imeyile (jonga kwicandelo elithi "Qhagamshelana" ukuze ufumane idilesi ye-imeyile).']

['I-DMCA ifuna ukuba isaziso sakho sokutyholwa ngokophula ilungelo lokushicilela siquke ezi nkcukacha zilandelayo: (1) inkcazelo yomsebenzi onelungelo lokushicilela ongundaba-mlonyeni wokutyholwa ngokophula; (2) inkcazelo yomxholo otyholwa ngokophula kunye nolwazi olwaneleyo ukusivumela ukuba sifumane umxholo; (3) iinkcukacha zokuqhagamshelana nawe, kuquka idilesi yakho, inombolo yomnxeba nedilesi ye-imeyile; (4) ingxelo yakho yokuba unokholo olulungileyo lokuba umxholo ngendlela ekhalazwa ngayo awugunyaziswanga ngumnini welungelo lokushicilela, okanye iarhente yakhe, okanye ngokusebenza kwawo nawuphi na umthetho; ']

['(5) ingxelo yakho, esayinwe phantsi kwesohlwayo sobuxoki, yokuba ulwazi olukwisibhengezo luchanekile kwaye unegunya lokunyanzelisa amalungelo okushicilela ekuthiwa aphulwe;']

['kwaye (6) utyikityo lomzimba okanye lwe-elektroniki lomnini welungelo lokushicilela okanye lomntu ogunyazisiweyo ukuba enze egameni lomnini welungelo lokushicilela. ']

['Ukungabandakanyi lonke ulwazi olungentla kungakhokelela ekulibaziseni ukuphathwa kwesikhalazo sakho.']

['Unxibelelwano']

['Nceda usithumelele i-imeyile ngayo nayiphi na imibuzo / iingcebiso.']

What are the risk factors for breast cancer?

There are several risk factors for breast cancer, some of which are modifiable and others that are not.

Here are some of the most common risk factors:

1. Age: The risk of developing breast cancer increases with age, with most cases occurring in women over the age of 50.

2. Family history: Having a close relative, such as a mother, sister, or daughter, with breast cancer increases your risk.

3. Genetic mutations: Certain inherited gene mutations, such as BRCA1 and BRCA2, increase the risk of developing breast cancer.

4. Reproductive history: Early menarche (start of menstruation), late menopause, and having no children or having the first child after age 30 can increase the risk.

5. Hormone replacement therapy: Long-term use of combined estrogen and progesterone hormone therapy after menopause can increase the risk.

6. Alcohol consumption: Drinking alcohol increases the risk of breast cancer.

7. Obesity: Being overweight or obese increases the risk, especially after menopause.

8. Physical activity: Lack of physical activity can increase the risk.

9. Radiation exposure: Exposure to high doses of radiation, particularly during childhood, can increase the risk.

10. Breast density: Women with dense breasts have a higher risk of developing breast cancer.

11. Menstrual history: Women who started menstruating early (before age 12) or went through menopause late (after age 55) have a slightly higher risk.

12. Breastfeeding: Women who have never breastfed have a slightly higher risk of developing breast cancer.

It is important to note that having one or more risk factors does not mean that a person will definitely develop breast cancer, and not having any risk factors does not guarantee that a person will not develop breast cancer.

However, understanding these risk factors can help individuals make informed decisions about their health and potentially reduce their risk.

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