What causes Colon cancer?

Fetí sí ojúewé yìí

Kí ló máa ń fa àrùn jẹjẹrẹ àgùntàn?

Àrùn jẹjẹrẹ àgùntàn, tí wọ́n tún ń pè ní àrùn jẹjẹrẹ àgùntàn, máa ń wáyé nítorí bí àwọn sẹ́ẹ̀lì tí kò bára dé ṣe ń dàgbà nínú àgùntàn àgùntàn tàbí àgùntàn àgùntàn.

A ò mọ ohun tó máa ń fa àrùn jẹjẹrẹ àgùntàn gan-an, àmọ́ àwọn nǹkan bíi mélòó kan lè mú kí ewu tó wà fún àìsàn náà pọ̀ sí i.

Lára àwọn nǹkan wọ̀nyí ni:

1. Ọ̀dọ́mọdé: Bí èèyàn bá ṣe ń dàgbà sí i, bẹ́ẹ̀ ni ewu àrùn jẹjẹrẹ ọ̀fun ńlá máa ń pọ̀ sí i, èyí tó pọ̀ jù lọ lára wọn ló sì ti lé ní ẹni àádọ́ta ọdún.

2. Ìtàn Ìdílé: Ìtàn Ìdílé tàbí Ìtàn Ìdílé tó ní àrùn jẹjẹrẹ àgùntàn tàbí àrùn polyps máa ń mú kí ewu àrùn náà pọ̀ sí i.

3. Àwọn àrùn tí wọ́n jogún: Àwọn àrùn kan tí wọ́n jogún, irú bí àrùn adenomatous polyposis (FAP) àti àrùn jẹjẹrẹ tí wọ́n jogún tí kì í ṣe àrùn polyposis colorectal cancer (HNPCC), lè mú kí ewu àrùn jẹjẹrẹ àgbo pọ̀ sí i.

4. Ọ̀nà tí wọ́n gbà ń gbé ìgbésí ayé: Ìjẹun tó pọ̀ gan-an nínú ẹran pupa àti ẹran tí wọ́n ti ṣe, fífọkànbalẹ̀, sìgá mímu, àti mímu ọtí líle gan-an lè mú kí àrùn jẹjẹrẹ àgùntàn pọ̀ sí i.

5. Àìsàn tí wọ́n ń pè ní inflammatory bowel disease: Àìsàn tí wọ́n ń pè ní inflammatory bowel disease, irú bí ulcerative colitis àti àìsàn Crohn, lè mú kí ewu àrùn jẹjẹrẹ àgbo pọ̀ sí i.

6. Àrùn àtọ̀gbẹ oríṣi kejì: Àwọn tó ní àrùn àtọ̀gbẹ oríṣi kejì ní ewu tó pọ̀ jù lọ láti ní àrùn jẹjẹrẹ ọ̀fun.

7. Ìtọ́jú Ìmọ́lẹ̀: Ìtọ́jú Ìmọ́lẹ̀ fún àwọn àrùn jẹjẹrẹ yòókù tó wà nínú ikùn lè mú kí ewu àrùn jẹjẹrẹ àgùntàn pọ̀ sí i.

8. Ẹ̀yà: Àwọn ọmọ ilẹ̀ Áfíríkà tó jẹ́ ọmọ ilẹ̀ Amẹ́ríkà ló máa ń ní àrùn jẹjẹrẹ àgùntàn ju àwọn èèyàn ẹ̀yà mìíràn lọ.

Ó ṣe pàtàkì láti ṣàkíyèsí pé lílo ọ̀kan tàbí jù bẹ́ẹ̀ lọ lára àwọn ohun tó ń fa ewu yìí kò túmọ̀ sí pé ẹnì kan máa ní àrùn jẹjẹrẹ àgùntàn, àwọn kan tó sì ní àrùn jẹjẹrẹ àgùntàn lè má ní nǹkan tó ń fa ewu kankan.

Ṣíṣe àyẹ̀wò déédéé àti ṣíṣàwárí kánkán lè ràn wá lọ́wọ́ láti dènà àrùn jẹjẹrẹ àgùntàn tàbí láti ṣàwárí rẹ̀ ní ìbẹ̀rẹ̀ nígbà tó bá ṣeé wo sàn jù lọ.

Àwọn ìtumọ̀

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

Ìyàsímímọ́: ìtọ́jú ìlera

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A ò gbọ́dọ̀ lo ìsọfúnni tó wà nínú ìwé náà láti ṣe àyẹ̀wò tàbí láti wo àìsàn tàbí àìsàn kan wò, àwọn tó bá sì ń wá ìmọ̀ràn nípa ìṣègùn fúnra wọn gbọ́dọ̀ bá dókítà tó ní ìwé àṣẹ sọ̀rọ̀.

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Ìyàsímímọ́: ẹ̀tọ́ ọmọnìyàn

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Ti o ba gbagbọ ni igbagbọ to dara pe eyikeyi akoonu tabi ohun elo ti o wa ni asopọ pẹlu oju opo wẹẹbu wa tabi awọn iṣẹ ṣe ilokulo aṣẹ-aṣẹ rẹ, iwọ (tabi aṣoju rẹ) le firanṣẹ akiyesi kan si wa ti o beere pe a yọ akoonu tabi ohun elo naa kuro, tabi idilọwọ iraye si rẹ.

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ati (6) ibuwọlu ti ara tabi itanna ti ẹni ti o ni aṣẹ tabi eniyan ti o ni aṣẹ lati ṣiṣẹ ni orukọ ẹni ti o ni aṣẹ.

Ti o ko ba ṣafikun gbogbo alaye ti o wa loke le ja si idaduro ti ṣiṣe ẹdun rẹ.

Ìfọ̀rọ̀wérọ̀

Jọwọ fi imeeli ranṣẹ si wa pẹlu eyikeyi ibeere / imọran.

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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