What are the risk factors for Alzheimer?

Lalela leli khasi

Yiziphi izici eziyingozi ze-Alzheimer's?

Kunezinto eziningana eziyingozi zesifo sika-Alzheimer, kuhlanganise:

1. Ubudala: Ingozi yokuthola isifo i-Alzheimer iyanda njengoba umuntu ekhula, futhi abantu abaningi bathola isifo ngemva kweminyaka engu-65.

2. Izakhi zofuzo: Ukuba nomlando womkhaya wesifo sika-Alzheimer noma ukuthwala izakhi zofuzo ezithile, njenge-APOE-e4 gene, kungandisa ingozi yokuthola lesi sifo.

3. Ukulimala ekhanda: Umlando wokulimala okukhulu ekhanda noma ukushaywa ingqondo kaningi kungase kwandise ingozi yesifo i-Alzheimer's.

4. Impilo yenhliziyo nemithambo yegazi: Izimo ezithinta inhliziyo nemithambo yegazi, ezifana nomfutho wegazi ophakeme, i-cholesterol ephezulu, isifo sikashukela nokukhuluphala ngokweqile, zingandisa ingozi yesifo sika-Alzheimer.

5. Izinto eziphathelene nendlela yokuphila: Ukubhema, ukuphuza ngokweqile, nokuntuleka kokuzivocavoca kungandisa ingozi yesifo sika-Alzheimer.

6. Ukungasebenzi kahle kwengqondo: Ukuntuleka kokugqugquzelwa kwengqondo namazinga aphansi emfundo kungase kwandise ingozi yesifo sika-Alzheimer.

7. Ukuphazamiseka kokulala: Ukuphazamiseka kokulala, njenge-sleep apnea, kungandisa ingozi yesifo i-Alzheimer's.

8. Izici ezingokwengqondo: Ukucindezeleka, ukucindezeleka, nokuzihlukanisa nabantu kungase kwandise ingozi yesifo sika-Alzheimer.

Kubalulekile ukuphawula ukuthi ukuba nesici esisodwa noma eziningi zalezi zici zobungozi akusho ukuthi umuntu uzoba nesifo se-Alzheimer's, futhi abanye abantu abangenazo izici zobungozi ezaziwayo basengaba nalesi sifo.

Nokho, ukuqonda lezi zici zobungozi kungasiza abantu ukuba bathathe izinyathelo zokunciphisa ubungozi babo futhi bathuthukise impilo yobuchopho.

Izikhombo

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

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What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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