Kanker usus besar, taler kauningin pinaka kanker kolorektal, mawinan panincapan sel abnormal sane nenten kakontrol ring usus besar utawi rektum.
Sane ngawinang kanker usus gede nenten kauningin, sakewanten makudang faktor sane prasida nincapang baya nglimbakang penyakit.
Puniki taler:
1. Umur: Risiko kanker usus besar sayan nincap nganutin yusa, katahan kasus ring anak sané sampun lintang saking 50 warsa.
2. Sejarah kulawarga: Sejarah pribadi utawi kulawarga kanker usus besar utawi polip nincapang risiko nglimbakang penyakit punika.
3. Sindrom warisan: Sindrom genetik warisan tertentu, sekadi familial adenomatous polyposis (FAP) miwah kanker kolorektal non-poliposis warisan (HNPCC), prasida nincapang risiko kanker usus besar.
4. Gaya hidup: Ngamah daging merah miwah daging olahan, lemu, ngrokok, miwah nginem alkohol akeh prasida nincapang risiko kanker usus besar.
5. Penyakit usus inflamasi: Penyakit usus inflamasi jangka panjang, sekadi ulcerative colitis miwah penyakit Crohn, prasida nincapang risiko kanker usus besar.
6. Diabetes tipe 2: Anak sané keni diabetes tipe 2 minab keni kanker usus besar.
7. Terapi radiasi: Terapi radiasi antuk kanker tiosan ring weteng prasida nincapang baya kanker usus besar.
8. Ras: Afrika Amerika madué risiko sané ageng ngamolihang kanker usus besar saking ras tiosan.
Penting pisan mangda uning indik madué asiki utawi akéh faktor risiko puniki nénten ja maarti jadma pacang keni kanker usus besar, miwah makudang-kudang anak sané keni kanker usus besar minab nénten madué faktor risiko sané kauningin.
Seseleh sane teratur miwah deteksi dini prasida ngawantu nyegah kanker usus besar utawi mendeteksi ring tahap awal rikala prasida kaobati.
McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.
Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.
Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.
Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.
Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.
Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.
Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.
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What causes colon cancer?
Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.
The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.
These include:
1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.
2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.
3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.
4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.
5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.
6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.
7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.
8. Race: African Americans have a higher risk of developing colon cancer than other races.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.
Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.
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