What causes Colon cancer?

['Ivwilila ku chihanda chino']

Yika yakuneha yikola yacho?

Cikola ya cancer ya mu mbolo hanji hanji mu mala, yakuneha kulioka cha ma celula waze keshi ni uhashi wa kulifunga mu mbolo hanji hanji mu mala.

Chuma chinene chakuneha yikola yacho kuchanyingikine, alioze kuli yuma yinji yize muyihasa kutohwesa yikola yacho.

Yize mikanda yiliho:

1. Musongo wa miaka: Musongo wa cancer ya mu jimo wakupwa chinji muze mutu anakukola, kanji-kanji wakupwa kuli atu waze ali ni miaka 50.

2. Usoko: Nyi mutu hanji asoko jenyi kali ni kansa ya ku mala hanji yikola yikwo, chino chakuneha yikola yacho.

3. Yikola ya mu usoko: Yikola yimwe ya mu usoko, ngwe, mutanga yoze uli ni yikola ya mu usoko (FAP) ni yikola ya mu mbolo yize kuyishi ni yikola ya mu mbolo (HNPCC), muyihasa kukolesa uhashi wa kupwa ni yikola ya mu mbolo.

4. Mutapu wa mwono: kulia yifwo yinji, kufula chinji, kunwa makanya ni kunwa chinji walwa, muchihasa kutohwesa yikola ya cancer ya mu jimo.

5. Yikola ya mu mala: Yikola ya mu mala yize yakupwa mashimbu anji, ngwe ulcerative colitis ni Crohn's disease, muyihasa kukolesa yikola ya cancer ya mu mala.

6. Musongo wa 2 wa shuga: Atu waze ali ni musongo wa 2 wa shuga kakupwa ni kansere ka mu jimo.

7. Uhashi wa kuchiza yikola ya cancer: Uhashi wa kuchiza yikola ya cancer mu jimo, muuhasa kutohwesa yikola ya cancer ya mu mbolo.

8. Vungu: A-Africa a ku América kali ni ponde yinji ya kupwa ni kansa ku chishimba kuhiana akwa mavungu akwo.

Chili chilemu kunyingika ngwo kupwa ni chimwe hanji yuma yinji yize yakuneha yikola yacho kuchalumbunuka ngwo mutu mamuka ni kansa ya musongo wa chinene, nawa atu amwe waze akupwa ni kansa ya musongo wa chinene mahasa kupwa ni yuma yize kuyishi ni ulemu.

Kuhengwola mashimbu eswe ni kuwana shimbu lieswayi muchihasa kukwasa hanga uhonese kansa ya musongo hanji uwane muze uchili upema hanga uwane yitumbo.

['Kuhanjika']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

['Ulemu: ukwaso wa yikola']

['Site yino kayitela hanga atu anyingike hakutwala ku yikola ni yikuma yikwo, kuyishi ni yiyulo ya mandotolo.']

['Sango jacho katambile kujizachisa hanga awane hanji awahise yikola, nawa waze anafupu yiyulo ya mandotolo katamba kuya kuli ndotolo.']

['Tala ha makina yize yakukwasa hanga uwane kumbululo lia yihula, hi yikalu ko muze anavuluka unji wa atu waze ali ni yikola.']

['Teta mashimbu eswe kuwana yiyulo ya ndotolo we hanji umwe mukwa-kuhana yiyulo ya uhayele ha chikuma cha yikola. Kanda ulionga yiyulo ya ndotolo hanji kutohwesa kuyitanga ha mukunda wa yimwe yuma yize watanga ha site yino. Nyi wanyonga ngwo uli ni mulonga wa uhayele, shinga 911 hanji yako ha chipatulo cha usopeso chize chili hakamwihi. Kukushi usepa wa ndotolo ni ndotolo uze wakunjila ha site yino hanji ha kuzachisa site yino. Chipwe BioMedLib hanji akwa-kukalakala nayo, hanji yoze wakukwasa ha site yino, keshi kulinga nichimwe, chipwe kusolola, hakutwala ku sango jize jili ha site yino hanji ha kuzachisa site yino.']

['Uhashi wa akwa-kusoneka']

['Shimbi ya Digital Millennium Copyright Act ya 1998, 17 U.S.C. § 512 (DMCA) yinambe ngwo, waze ali ni shimbi ja akwa-kusoneka waze anafuliela ngwo yuma yize yili ha Internet yinapinjisa shimbi ja akwa-kusoneka ja mu Estados Unidos. ']

['Nyi unafuliela ni mbunge yeswe ngwo yikuma yeswe yize akuzachisa ha site yino yinapinjisa shimbi ja akwa-kusoneka, yena (mba yoze wakuzachisa) muhasa kututumina mukanda hanga ututuhwise yikuma yacho hanji kuhona kuyimona.']

['Sango jacho katamba kujituma ha mukanda ha email (tala ha chihanda cha "Contact" ha email).']

['Shimbi ya DMCA yinambe ngwo, sango je ha yize akuhanjika ngwo yapinjisa shimbi ja akwa-kusoneka yili ni sango jacho: (1) kulumbununa mulimo uze uli ni shimbi ja akwa-kusoneka uze anazangamisa; (2) kulumbununa yikuma yize anazangamisa ni sango jize jinahase kutukwasa hanga tuwane yikuma yacho; (3) kulweza yoze mutuhasa kumuheta, ngwe adresi, numero ya telefone ni email; (4) maliji waze yena musolola ngwo, yuma yize anazangamisa kuyishi ni utayizo wa mwene wa shimbi ja akwa-kusoneka, hanji yoze akuzachisa, hanji ni shimbi jize anazangamisa; ']

['(5) Sango jize yena musoneka, ni shimbi jize makahana, ngwo sango jize jili ha mukanda jili ja umwenemwene nawa uli ni ulite wakukwasa hanga akwa-kusoneka afunge shimbi jize anakwambulula ngwo jinalitepulula;']

['nawa (6) chijimbikilo cha mwata wa shindakenyo ya ulite wa yuma hanji cha muthu yoze uli ni ulite wa kulinga yuma ha jina lia mwata wa shindakenyo ya yuma.']

['Nyi kuhona kusa sango jacho mu mukanda, kuchihasa kutohwesa chikuma chikuma.']

['Kulitakana']

['Tutuminenu mukanda ni yihula ni yiyulo yenu.']

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.

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