Dɔdzẽ ƒe dɔléle ŋuti nunya fia alesi dɔdzẽ wɔna tsinae.
Dɔdzẽ si woyɔna be colon cancer, si wogayɔna be colorectal cancer, nye dɔdzẽ ƒomevi aɖe si dzea egɔme tso colon alo rectum, si nye dɔkavi gã ƒe akpa aɖe.
Zi geɖe la, edzea egɔme tso nu sue aɖe si woyɔna be polyp, si ate ŋu ava zu kansa le ɣeyiɣi aɖe megbe.
Dɔlékui siwo nana ame léa dɔdzẽ la dometɔ aɖewoe nye domenyiŋusẽfianu ƒe tɔtrɔ, dɔléle, kple nutome ƒe nɔnɔme.
Domenyiŋusẽfianu ƒe tɔtrɔ ate ŋu adzɔ le lãmenugbagbevi siwo le dɔkavi me ƒe DNA me, si ana lãmenugbagbeviwo nadzi ɖe edzi eye woama le wo ɖokui si.
Dzɔdzɔmeŋusẽfianu ƒe tɔtrɔ siawo ate ŋu anye esiwo ƒe dome ame nyi alo esiwo wòxɔna, eye woate ŋu akpɔ ŋusẽ ɖe domenyiŋusẽfianu vovovo siwo kpɔa gome le lãmenugbagbeviwo ƒe tsitsi, mamã, kple wo dzadzraɖo me la dzi.
Dɔléle siwo nana dɔ sia dzea ame dzi abe dɔxɔleameŋu si nana dɔ sia dzea ame dzi ene hã ate ŋu ana dɔ sia nadze ame dzi.
Dzidede atraɖii ate ŋu ana lãmetsi siwo nana lãmenugbagbeviwo tsina hetsoa akpa la nado, eye esia ate ŋu ana kansa nadze ame dzi.
Nanewo abe nuɖuɖu, agbenɔnɔ, kple atike aɖewo zazã hã ate ŋu ana dɔ sia nadze ame dzi.
Le kpɔɖeŋu me, wode dzesii be nuɖuɖu siwo me lã dzĩ kple esiwo ŋu wotrɔ asi le le fũ ate ŋu ana ame nalé dɔdzẽ.
Nu bubuwo abe lolo akpa, atamanono, kple kamedede fũu akpa hã ate ŋu ana afɔku sia nadzi ɖe edzi.
Ne dɔdzẽ do le dɔ me na ame ko la, etea ŋu yia ŋgɔ le akpa vovovowo me, tso dɔdzẽ si le dɔ me nɛ ƒe gɔmedzedze dzi vaseɖe esi me dɔdzẽa kaka ɖe ŋutilã ƒe akpa bubuwo dzi.
Lãmenugbagbevi siwo me kansa le ate ŋu adze lãmekawo kple ŋutinu siwo te ɖe wo ŋu dzi, eye ate ŋu akaka to ʋukawo me ayi teƒe siwo didi abe aklã alo dzitodzito ene.
Dɔdzẽ ƒe dɔdamɔnu si woyɔna be colon cancer la lɔa dɔ wɔwɔ, atike siwo wotsɔna daa dɔe, kple keklẽŋusẽ tsɔtsɔ daa dɔe ɖe eme, eye esia nɔa te ɖe dɔdzẽa ƒe tsitsi kple afi si wòle dzi.
Dɔlélea kpɔkpɔ kaba kple atikewɔwɔe nye nu vevi si ana woada dɔa kaba, elabena woate ŋu ada dɔ sia kaba.
Ne èléa ŋku ɖe wò dɔkaviwo ŋu edziedzi, abe ne èle nu me kpɔm ene la, ate ŋu akpe ɖe ŋuwò nàkpɔ dɔkavi me kansa kaba, esime woate ŋu adae bɔbɔe wu.
Vidal-Vanaclocha F: The liver prometastatic reaction of cancer patients: implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron. 2011, 4 (2): 163-80.
Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
['Mɔxeɖenu: atikewɔwɔ']
['Taɖodzinu siwo nye nufiafia kple nyatakaka koe le nyatakakadzraɖoƒe sia ŋu eye menye atikewɔwɔ ŋuti ɖaŋuɖoɖo alo dɔwɔnawo ƒe nya gblɔm wole o.']
['Mele be woazã nyatakaka siwo wona la atsɔ ada dɔléle alo dɔ aɖe o, eye ele be amesiwo di be yewoakpɔ atikewɔwɔ ŋuti ɖaŋuɖoɖo na yewo la nabia ɖɔkta si xɔ mɔɖegbalẽ.']
['De dzesii be neural network si wɔa nyabiabiawo ƒe ŋuɖoɖowo la meɖia o vevietɔ ne wotsɔ xexlẽdzesiwo wɔe. Le kpɔɖeŋu me, ne wotsɔ ame siwo ŋu dɔléle aɖe le ƒe xexlẽme wɔ dɔe.']
['Bia wò ɖɔkta alo lãmesẽdɔwɔla bubu si dze ƒe aɖaŋuɖoɖo ɣesiaɣi le lãmesẽkuxi aɖe ŋu. Mègaŋe aɖaba ƒu aɖaŋuɖoɖo si ɖɔktawo ɖo na wò alo gbɔ dzi ɖi le exexlẽ me le nyatakakadzraɖoƒe sia ta o. Ne èsusu be ɖewohĩ lãmesẽkuxi aɖe le fu ɖem na ye la, ke yɔ 911 alo yi ɖe afisi wokpɔa nɔnɔme kpatawo gbɔ le.']
['Copyright: Copyright']
['Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the DMCA) na mɔ siwo dzi copyright ƒe nunɔlawo ate ŋu ato awɔ nu ɖe nu siwo wo xɔ se be wo le Internet dzi la ŋu.']
['Ne èxɔe se kple kakaɖedzi be nyatakakadzraɖoƒe alo dɔwɔnu aɖe si míetsɔ wɔ míaƒe nyatakakadzraɖoƒea alo dɔwɔnawo la nye dada le wò gome la, wò ŋutɔ (alo wò dɔtɔ) ate ŋu aŋlɔ agbalẽ aɖo ɖe mí abia be míaɖe nyatakakadzraɖoƒea alo dɔwɔnua ɖa alo axe mɔ ɖe ezazã nu.']
['Ele be woana nyatakakawo to e-mail dzi (kpɔ "Kpekpeɖeŋunaƒe" ƒe akpa si nye e-mail adrɛs). ']
['DMCA bia be nàŋlɔ nyatakaka siwo gbɔna ɖe wò nyatakaka si nèŋlɔ be woada le copyright dzi la me: (1) nuŋɔŋlɔ si fia be copyright le dɔ si ŋu wole nu ƒom le la ŋu; (2) nyatakaka si fia be nuŋɔŋlɔa le eme eye wòade mía nu be míake ɖe eŋu; (3) nyatakaka siwo ana míake ɖe ŋuwò, siwo dometɔ aɖewoe nye wò adrɛs, kaƒodzesi kple e-mail adrɛs; (4) wò nya si fia be èxɔe se kple kakaɖedzi be copyright ƒe ame si tɔe nyatakakaa nye, alo eƒe dɔtɔ, alo se aɖeke meɖe mɔ ɖe eŋu o; ']
['(5) Wò ŋutɔ nàŋlɔ agbalẽ si dzi nàde asii, si me nàde se be ne mèwɔe o la, àda alakpa, atsɔ aɖo kpe edzi be nyatakaka siwo le nyatakakaa me la de pɛpɛpɛ eye be ŋusẽ le asiwò be nàʋli agbalẽ siwo ŋu wogblɔ le be woda le la ta.']
['Eye (6) ame si tɔe agbalẽa nye alo ame si wona ŋusẽe be wòawɔ dɔ le ame si tɔ ŋkɔ me la ƒe asinuŋɔŋlɔ alo eƒe asinuŋɔŋlɔ si le mɔ̃ dzi. ']
['Ne mèŋlɔ nyatakaka siwo katã le etame ɖe agbalẽa me o la, ate ŋu ana be wò nyatoƒoe me dzodzro natsi megbe.']
['Kadodo']
['Taflatse ɖo email ɖe mí ne nyabiabia alo aɖaŋuɖoɖo aɖe le asiwò.']
What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
Disclaimer: medical
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Disclaimer: copyright
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['Le Eŋu']
['BioMedLib zãa kɔmpiuta siwo wɔa dɔ le wo ɖokui si (mɔ̃ siwo zãa mɔ̃ɖaŋunuwo tsɔ srɔ̃a nu) tsɔ wɔa nyabiabia kple ŋuɖoɖowo.']
