Ti kanser iti bagis, a pagaammo met kas colorectal cancer, ket gapu iti di makontrol a panagdakkel dagiti abnormal a selula iti bagis wenno rectum.
Saan nga ammo ti eksakto a pakaigapuan ti kanser iti bagis, ngem adda sumagmamano a banag a mangpakaro iti peggad ti panagsakit.
Dagitoy ti pakairamanan:
1. Edad: Umad-adu ti agsakit iti kanser ti bagis bayat nga agmataengan ti maysa, a kaaduan a tattao nga agsakit iti dayta ket agtawen iti nasurok a 50.
2. Pakasaritaan ti pamilia: Ti personal wenno pakasaritaan ti pamilia iti kanser ti bagis wenno polyp ti mangpadakkel iti peggad a maaddaan iti sakit.
3. Dagiti natawid a sakit: Dadduma a natawid a sakit a kas iti familial adenomatous polyposis (FAP) ken hereditary non-polyposis colorectal cancer (HNPCC), ti mangpakaro iti posibilidad a maaddaan iti kanser ti bagis.
4. Estilo ti panagbiag: Ti pannangan iti adu a karne, kinalukmeg, panagsigarilio, ken nalabes a panaginum iti arak ti mabalin a mangpakaro iti posibilidad nga agkanser ti bagis.
5. Inflammatory bowel disease: Dagiti napaut a sakit ti bagis, kas iti ulcerative colitis ken Crohn's disease, mabalin a mangpakaro iti peggad ti kanser ti bagis.
6. Type 2 diabetes: Dagiti addaan iti type 2 diabetes ket dakdakkel ti posibilidadna nga agsakit iti kanser ti bagis.
7. Radiation therapy: Ti radiation therapy para iti dadduma a kanser iti tian mabalin a mangpadakkel iti peggad ti kanser iti bagis.
8. Rasa: Dagiti Africano nga Americano ti ad-adda a maaddaan iti kanser ti bagis ngem kadagiti dadduma a rasa.
Napateg a laglagipen a ti kaadda ti maysa wenno ad-adu pay kadagitoy a pakaigapuan ti panagsakit dina kaipapanan a maaddaan ti maysa a tao iti kanser iti bagis, ken mabalin nga awan ti aniaman a pakaigapuan ti panagsakit ti dadduma a tattao a maaddaan iti kanser iti bagis.
Ti regular a panageksamen ken nasapa a panangilasin ket makatulong a manglapped iti kanser iti bagis wenno mangilasin iti dayta iti nasapa a pasetna no mabalin unay a maagasan.
McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.
Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.
Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.
Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.
Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.
Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.
Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.
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What causes colon cancer?
Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.
The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.
These include:
1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.
2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.
3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.
4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.
5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.
6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.
7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.
8. Race: African Americans have a higher risk of developing colon cancer than other races.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.
Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.
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