Ana sawetara pilihan perawatan sing kasedhiya kanggo kanker prostat, gumantung saka tahap lan agresifitas kanker, uga kesehatan umum lan pilihan pribadi pasien.
Sawetara perawatan umum kalebu:
1. Pengawasan aktif: Pendekatan iki kalebu ngawasi kanker kanthi tliti kanthi mriksa lan tes rutin, tinimbang langsung miwiti perawatan.
Bisa uga cocog kanggo wong lanang sing duwe kanker prostat kanthi risiko sithik.
2. Pembedahan: Prostatektomi minangka prosedur bedah kanggo mbusak kelenjar prostat.
Iki bisa ditindakake liwat operasi terbuka utawa laparoskopi (nggunakake sayatan cilik lan alat khusus).
3. Terapi radiasi: Perawatan iki migunakaké radiasi energi dhuwur kanggo matèni sel kanker.
Bisa dikirim ing njaba (saka mesin ing njaba awak) utawa ing njero (liwat implan sing diselehake ing sacedhake tumor).
4. Terapi hormon: Perawatan iki nyuda tingkat hormon lanang (androgen) ing awak, sing bisa nyuda utawa mungkasi tuwuhing kanker prostat.
Bisa digunakake piyambak utawa ing kombinasi karo perawatan liyane.
5. Kemoterapi: Perawatan iki migunakaké obat-obatan kanggo matèni sel kanker.
Bisa digunakake kanggo kanker prostat sing wis maju sing wis nyebar menyang bagean awak liyane.
6. Imunoterapi: Perawatan iki mbantu sistem kekebalan awak nglawan kanker.
Bisa digunakake kanggo kanker prostat sing wis maju sing ora nanggapi perawatan liyane.
7. Terapi sing ditargetake: Perawatan iki ngarahake gen utawa protein tartamtu sing mbantu sel kanker tuwuh lan urip.
Bisa digunakake kanggo kanker prostat sing wis maju sing ora nanggapi perawatan liyane.
8. Cryotherapy: Perawatan iki nggunakake kadhemen banget kanggo beku lan mateni sel kanker.
Bisa digunakake kanggo kanker prostat tahap awal utawa kanggo kanker sing wis bali sawise perawatan liyane.
9. Ultrasound fokus intensitas dhuwur (HIFU): Perawatan iki nggunakake gelombang swara frekuensi dhuwur kanggo panas lan ngrusak sel kanker.
Bisa digunakake kanggo kanker prostat tahap awal utawa kanggo kanker sing wis bali sawise perawatan liyane.
10. Ngenteni kanthi ati-ati: Pendekatan iki kalebu ngawasi kanker kanthi tliti kanthi mriksa lan tes rutin, nanging ora miwiti perawatan kajaba gejala katon utawa owah.
Bisa uga cocog kanggo pria sing luwih tuwa kanthi kanker prostat sing tuwuh alon lan kondisi kesehatan sing serius liyane.
Penting kanggo ngrembug kabeh pilihan perawatan karo tim perawatan kesehatan kanggo nemtokake tumindak sing paling apik kanggo saben kasus individu.
Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.
Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.
Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.
Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.
Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.
de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.
Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.
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How to treat prostate cancer?
There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.
Some common treatments include:
1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.
It may be suitable for men with low-risk prostate cancer.
2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.
It can be done through open surgery or laparoscopically (using small incisions and specialized tools).
3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.
It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).
4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.
It can be used alone or in combination with other treatments.
5. Chemotherapy: This treatment uses drugs to kill cancer cells.
It may be used for advanced prostate cancer that has spread to other parts of the body.
6. Immunotherapy: This treatment helps the immune system fight cancer.
It may be used for advanced prostate cancer that has not responded to other treatments.
7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.
It may be used for advanced prostate cancer that has not responded to other treatments.
8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.
It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.
It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.
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