What causes Colon cancer?

['Widikila lutiti yai']

Inki kebasisaka kansere ya mukwa ya nene?

Kansere ya mukwa ya nene, to kansere ya mukwa ya nene, ke basikaka ntangu baselile ya mbi ke yelaka mingi na mukwa ya nene to na mukwa ya nene.

Bantu ke zabaka ve nki ke salaka nde muntu kukuma ti kansere ya mukwa ya nene, kansi mambu mingi lenda sala nde muntu kukuma ti kansere.

Mambu yango kele:

1. Bamvula: Kana muntu ke na bamvula mingi, yandi lenda kuma ti kansere ya nene, mpi bantu mingi kebelaka yo kana bo meluta bamvula 50.

2. Bantu yina kele ti kansere ya divumu na dibuta: Kana muntu mosi to bantu ya dibuta na yandi kele ti kansere ya divumu to ti maladi ya mutindu yai, yo kekumisaka kigonsa ya maladi yai ngolo.

3. Maladi yina muntu kebutukaka ti yo: Maladi yankaka ya bantu kebutukaka ti yo, mu mbandu maladi ya bo kebingaka adenome ya polypose (FAP) mpi kansere ya nene ya divumu (HNPCC), lenda sala nde muntu kukuma ti kansere ya nene ya divumu.

4. Mutindu ya luzingu: Madya yina kele ti misuni mingi ya mbwaki mpi ya bo mesala na bima ya nkaka, nene ya kuluta ndilu, kunwa makaya, mpi kulauka malafu lenda sala nde muntu kukuma ti kansere ya nene.

5. Maladi ya misopo: Kana muntu kebela maladi ya misopo na nsungi ya nda, mu mbandu maladi ya bo kebingaka colite ulcéreuse mpi maladi ya Crohn, yo lenda sala nde yandi kuma ti kansere ya misopo.

6. Diabete ya mutindu ya zole: Bantu yina kebelaka diabete ya mutindu ya zole kevandaka na kigonsa ya ngolo ya kukuma ti kansere ya nene.

7. Kusadila radiothérapie: Kusadila radiothérapie sambu na maladi yankaka ya kansere ya divumu lenda sala nde muntu kukuma ti kansere ya nene.

8. Mpusu ya nitu: Bantu ya Afrika ya Amerika kevandaka na kigonsa ya ngolo ya kubaka kansere ya nene kuluta bantu ya bampusu yankaka.

Yo kele mfunu na kuzaba nde kana muntu kele ti kima mosi to mambu mingi ya ke nata yandi na maladi yai, yo ke tendula ve nde yandi ta kuma ti kansere ya nene ya divumu.

Kana bo kesadila ekzame mbala na mbala mpi bo kesengumuna yo na luyantiku, yo lenda sadisa na kubuya kansere ya nene to na kuzaba yo na luyantiku ntangu yo kele mpasi ve na kubelula yo.

['Baverse ya nkaka']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

['Disclaimer: mambu ya kimunganga']

['Site Internet yai kele kaka sambu na kulonga mpi kupesa bansangu, kansi yo kele ve sambu na kupesa bandongisila ya minganga to kusadila bantu ya nkaka kisalu.']

['Bo fwete sadila ve bansangu yina bo kepesa sambu na kuzaba to kubelula maladi mosi buna, mpi bantu yina kesosa bandongisila ya kimunganga fwete solula ti munganga yina kele ti nswa ya kusala kisalu yina.']

['Tala nde, ba-apareyi yina ke pesaka bamvutu na bangiufula ke vandaka ve mbote ntangu bo ke sadilaka ntalu, mu mbandu ntalu ya bantu yina bo me zaba nde bo ke belaka maladi mosi buna.']

['Sosa ntangu yonso bandongisila ya munganga to ya muntu ya nkaka ya me zaba kisalu ya kusansa bantu sambu na maladi na nge. Kuvila ve bandongisila ya munganga to kusukinina ve na kusosa yo sambu na mambu ya nge me tanga na site Internet yai. Kana nge ke yindula nde nge kele ti maladi ya ngolo, binga 911 to kwenda nswalu na lupitalu ya me finama. Site Internet yai to mutindu nge ke sadila yo ke sala ve nde nge kuma nduku ya munganga to nkengi ya maladi.']

['Banswa ya kusonika']

['Nsiku ya Banswa ya Bansoniki ya Internet ya mvu 1998, 17 U.S.C. § 512 (DMCA) ke pesa nswa na bantu yina kele ti banswa ya bansoniki ya ke kwikila nde mambu yina ke monana na Internet ke fwa banswa na bo na nsi ya nsiku ya banswa ya bansoniki ya États-Unis. ']

['Kana nge ke mona nde mambu ya nge ke tanga na site Internet na beto to na baservice na beto ke fwa banswa na nge, nge (to muntu yina ke twadisaka nge) lenda tindila beto mukanda sambu na kulomba nde beto katula yo to kukanga nzila na nge ya kusadila yo.']

['Bo fwete tinda bansangu na mukanda na nzila ya email (tala na "Kutuba na beto" sambu na kuzaba adresi ya email).']

['Nsiku ya DMCA ke lomba nde na mukanda na nge ya ke tubila nde bo me fwa nsiku ya banswa ya bantu, nge sonika mambu yai: (1) mutindu ya kutendula kisalu yina bo me fwa nsiku; (2) mutindu ya kutendula mambu yina bo me fwa nsiku mpi bansangu yina ta sadisa beto na kuzaba kisika yina mambu yango kele; (3) bansangu ya nge lenda sadila sambu na kusolula ti nge, tanga mpi adresi na nge, nimero ya telefone mpi adresse ya e-mail; (4) mambu ya nge me tuba nde nge ke kwikila nde mambu yina nge ke tuba kele ve na nswa ya munkwa-kisalu to muntu yina me pesa nswa na yo to na nsiku ya leta.']

['5) na nima ya kupesa nzikisa na mukanda yina nge me sonika, nge fwete ndima nde mambu yina nge me tuba kele ya kieleka mpi nde nge kele ti nswa ya kusadila banswa yina bo me bebisa.']

['mpi (6) kidimbu ya muntu yina kele ti nswa ya kubasisa yo to ya muntu yina kele ti nswa ya kusala mambu na zina na yandi. ']

['Kana nge pesa ve bansangu yai yonso, yo lenda sala nde bo sala ve mambu nswalu.']

['Kusolula']

['Beno tindila beto email kana beno kele na ngyufula to ngindu.']

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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