What causes Prostate cancer?

Apo panyababnyo kanker prostat?

panyakik prostat ko indak dikatahui jo pasti, tapi ado babarapo faktor nan dapek maningkekan risiko panyakik ko.

Di antaronyo adolah:

1. Umua: Risiko kanker prostat batambah jo umua, jo sabagian gadang kasus tajadi pado laki-laki nan baumua labiah dari 65 taun.

2. Sijarah kaluarga: Laki-laki nan ado sijarah kaluarga nan punyo kanker prostat, tarutamo ayah atau adiak laki-laki nan punyo panyakik ko, labiah barisiko.

3. Raso: Laki-laki Afrika Amerika labiah barisiko dapek kanker prostat daripado laki-laki dari raso lain.

4. Makanan: Makanan nan banyak lemak, tarutamo lemak binatang, dapek maningkekan risiko kanker prostat.

5. Kacimburuan: Kacimburuan dapek maningkekkan risiko panyakik kanker prostat.

6. Hormon: Tingkek testosteron jo hormon laki-laki lainnyo nan tinggi dapek maningkekan risiko kanker prostat.

7. Radang: Radang prostat nan kronis, sarupo prostatitis, dapek maningkekkan risiko kanker prostat.

8. Genetik: Mutasi genetik tatantu nan diwariskan, sarupo nan ado di gen BRCA1 jo BRCA2, dapek maningkekan risiko kanker prostat.

Paralu diingek baso ado ciek atau labiah faktor risiko ko indak baarati laki-laki pasti akan manganduang kanker prostat, dan banyak laki-laki jo kanker prostat indak punyo faktor risiko nan dikatahui.

Salain itu, panalitian sadang dilakuan untuak labiah mangarati panyabab kanker prostat jo manantuan faktor risiko lainnyo.

['Rujuakan']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Riihimäki M, Thomsen H, Brandt A, Sundquist J, Hemminki K: What do prostate cancer patients die of? Oncologist. 2011, 16 (2): 175-81.

Gilligan T: Social disparities and prostate cancer: mapping the gaps in our knowledge. Cancer Causes Control. 2005, 16 (1): 45-53.

Newschaffer CJ, Otani K, McDonald MK, Penberthy LT: Causes of death in elderly prostate cancer patients and in a comparison nonprostate cancer cohort. J Natl Cancer Inst. 2000, 92 (8): 613-21.

Frydenberg M, Wijesinha S: Diagnosing prostate cancer - what GPs need to know. Aust Fam Physician. 2007, 36 (5): 345-7.

Shimodaira K, Nakashima J, Nakagami Y, Hirasawa Y, Hashimoto T, Satake N, Gondo T, Namiki K, Ohori M, Ohno Y: Prognostic Value of Platelet Counts in Patients with Metastatic Prostate Cancer Treated with Endocrine Therapy. Urol J. 2020, 17 (1): 42-49.

Martínez-Salamanca JI, Ballesteros CM, Carballido Rodríguez J: [Epidemiological fundamentals of clinically localized prostate cancer]. Arch Esp Urol. 2011, 64 (8): 703-10.

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What causes prostate cancer?

The exact cause of prostate cancer is not known, but several factors have been identified that may increase the risk of developing the disease.

These include:

1. Age: The risk of prostate cancer increases with age, with most cases occurring in men over the age of 65.

2. Family history: Men with a family history of prostate cancer, particularly a father or brother with the disease, are at a higher risk.

3. Race: African American men have a higher risk of developing prostate cancer than men of other races.

4. Diet: A diet high in fat, particularly animal fat, may increase the risk of prostate cancer.

5. Obesity: Being overweight or obese may increase the risk of developing prostate cancer.

6. Hormones: High levels of testosterone and other male hormones may increase the risk of prostate cancer.

7. Inflammation: Chronic inflammation of the prostate, such as prostatitis, may increase the risk of prostate cancer.

8. Genetics: Certain inherited genetic mutations, such as those in the BRCA1 and BRCA2 genes, may increase the risk of prostate cancer.

It is important to note that having one or more of these risk factors does not mean that a man will definitely develop prostate cancer, and many men with prostate cancer have no known risk factors.

Additionally, research is ongoing to better understand the causes of prostate cancer and identify additional risk factors.

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