Ko te Pathophysiology o te mate huka e pa ana ki te ako i nga tikanga o te tinana e arahi ana ki te whanaketanga o te mate huka.
Ko te mate huka he rōpū o ngā mate pūkoro e tohu ana i ngā taumata huka toto tiketike (tūhuka) e hua mai ana i ngā hē i roto i te tukunga insulin, te mahi insulin, ngā mea e rua rānei.
Ko te pathophysiology o te mate huka e pa ana ki te whakawhitinga matatini o nga ira, o te taiao, me nga ahuatanga o te oranga e uru ana ki te whanaketanga o te mate.
I te mate huka momo 1, ko te pathophysiology e pa ana ki te whakangaromanga autoimmune o nga pūtau beta e whakaputa ana i te insulin i roto i te pancreas, ka heke te hanga o te insulin.
Ko te hua o tēnei he kore e taea te whakahaere i ngā taumata huka toto, e ahu atu ana ki te hyperglycemia (te huka toto tiketike).
I te mate huka momo 2, he uaua ake te pathophysiology, ka uru ki te aukati i te insulin me te ngoikoretanga o te insulin.
Ka puta te ātete o te insulin ina kore e tika te urupare o nga pūtau o te tinana ki te insulin, ka kore e taea te whakamahi tika i te huka hei pūngao.
Mā tēnei e whakaputa ai te pūkahukahu i te nui ake o te insulin hei whakamātau ki te wikitoria i te ātete, engari i te roanga o te wā, kāore pea te pūkahukahu e kaha ki te pupuri i te tono, e ahu ana ki te heke o te whakaputa insulin.
Ko te mate huka hapūtanga, ka puta i te wā e hapū ana, nā ngā huringa taiaki e ahu atu ana ki te ātete o te insulin.
Ka whakaputaina e te kōpae ngā taiaki e ārai ai i te mahi o te insulin, e piki ai ngā taumata huka toto.
Ko te pathophysiology o te mate huka e pa ana ki te whanaketanga o nga raru, penei i te kino o nga oko toto, nga io, me nga okana, ka raru pea te hauora penei i te mate ngakau, te whiu, te mate whatukuhu, me te ngaro o te tirohanga.
Ko te mārama ki te pathophysiology o te mate huka he mea nui ki te whakawhanake i ngā maimoatanga whai hua me ngā rautaki ārai mō tēnei mate ma'i.
Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.
Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.
Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.
Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.
Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.
Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.
['Whakakahoretanga: hauora']
['Ko tenei paetukutuku e whakaratohia ana mo nga kaupapa ako me nga korero anake, kaore hoki e whakarato i nga tohutohu hauora, i nga ratonga ngaio ranei.']
['Kaua e whakamahia ngā mōhiohio e whakaratohia ana hei tātaritanga, hei whakaora rānei i tētahi raruraru hauora, mate rānei, ā, ko te hunga e rapu ana i te tohutohu hauora whaiaro me kōrero ki tētahi tākuta whai raihana.']
['Kia mōhio mai koe ko te whatunga pūtau e whakaputa ana i ngā whakautu ki ngā pātai, he tino hē ina tae mai ki te ihirangi tau. Hei tauira, ko te tokomaha o ngā tāngata kua tohua he mate tauwhāiti.']
['Me rapu tonu i te tohutohu a tō tākuta, i tētahi atu kaiwhakarato hauora whai tohu rānei e pā ana ki tētahi mate hauora. Kaua rawa e whakahawea ki te tohutohu hauora ngaio, te whakaroa rānei ki te rapu i te mea nā tētahi mea i pānuihia e koe i tēnei paetukutuku. Ki te whakaaro koe he mate hauora ohorere pea koe, waea atu ki te 911 ka haere ki te rūma ohorere tata tonu. Kāore he hononga tākuta-tūroro i hangaia e tēnei paetukutuku, i tōna whakamahinga rānei. Kāore a BioMedLib, ōna kaimahi rānei, tētahi kaitohutohu rānei ki tēnei paetukutuku, e whakaatu ana, e tohu ana rānei, e pā ana ki ngā mōhiohio e whakaratohia ana i konei, ki tōna whakamahinga rānei.']
['Whakakahoretanga: mana pupuri']
['Ko te Ture Mana pupuri Mamati Mamati o te tau 1998, 17 U.S.C. § 512 (te DMCA) e whakarato ana i te whakahoki mo nga rangatira mana pupuri e whakapono ana ko nga rauemi e puta ana i runga i te Ipurangi e takahi ana i o raatau mana i raro i te ture mana pupuri a US. ']
['Mēnā e whakapono pono ana koe e takahi ana tētahi ihirangi, rauemi rānei e wātea ana i runga i tō mātou paetukutuku, ratonga rānei i tō mana pupuri, ka taea e koe (tō māngai rānei) te tuku pānui ki a mātou e tono ana kia tangohia te ihirangi, rauemi rānei, kia āraia rānei te uru atu ki a ia. ']
["Me tuku ngā whakamōhiotanga ā-tuhi mā te īmēra (tirohia te wāhanga 'Whakapā' mō te wāhitau īmēra). "]
['E hiahiatia ana e te DMCA kia whakaurua ki tō whakamōhiotanga mō te whakawātea mana pupuri i ngā mōhiohio e whai ake nei: (1) whakaahuatanga o te mahi mana pupuri e pā ana ki te whakawātea e whakapaetia ana; (2) whakaahuatanga o te ihirangi e whakapaetia ana e takahi ana me ngā mōhiohio e tika ana kia taea ai e mātou te kimi i te ihirangi; (3) mōhiohio whakapā mōu, tae atu ki tō wāhitau, tau waea me tō wāhitau īmēra; (4) he tauākī nāu e whakapono pono ana koe kāore te ihirangi i te āhua e amuamutia ana i whakamanahia e te kaipupuri mana pupuri, e tana māngai rānei, e te whakahaerenga rānei o tētahi ture; ']
['(5) he tauākī nāu i haina, i raro i te whiu o te whakapae teka, e tika ana ngā mōhiohio i roto i te whakamōhiotanga, ā, kei a koe te mana ki te whakatinana i ngā mana pupuri e kīia ana kua takahia;']
['me te (6) he waitohu ā-tinana, ā-rorohiko rānei a te kaipupuri mana pupuri, a tētahi tangata rānei kua whakamanahia ki te mahi mō te kaipupuri mana pupuri. ']
['Ki te kore e whakaurua ngā mōhiohio katoa i runga ake nei, ka whakaroa pea te tukatuka o tō amuamu.']
['Whakapā']
['Tena koa tukuna mai he imeera ki a maatau me tetahi patai / whakaaro.']
What is pathophysiology of diabetes?
Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.
The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.
In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.
This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).
In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.
Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.
This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.
Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.
The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.
The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.
Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.
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['Mō te']
['Ka whakamahi a BioMedLib i nga rorohiko aunoa (nga hātepe ako-mīhini) hei whakaputa takirua pātai-me-whakautu.']
['Ka tīmata mātou ki te 35 miriona ngā tānga rongoā koiora o PubMed/Medline.']
['Tirohia te "Whakaputanga" hoki "Whakakahoretanga".']