How to treat Prostate cancer?

['Mamela leqephe lena']

Kankere ea tšoelesa ea senya e phekoloa joang?

Ho na le mekhoa e'maloa ea phekolo e fumanehang bakeng sa kankere ea tšoelesa ea senya, ho itšetlehile ka boemo le ho ba matla ha kankere, hammoho le bophelo bo botle ka kakaretso ba mokuli le lintho tseo a li ratang.

Mekhoa e meng e tloaelehileng ea ho phekola e akarelletsa:

1. Ho hlahloba ka hloko: Mokhoa ona o akarelletsa ho hlahloba kankere ka hloko ka ho e hlahloba le ho e hlahloba kamehla, ho e - na le ho qala kalafo hang - hang.

E ka 'na ea e-ba e loketseng banna ba nang le kankere ea tšoelesa ea senya e kotsi.

2. Ho buoa: Ho ntšoa ha tšoelesa ea senya ke mokhoa oa ho buoa o etsoang ho tlosa tšoelesa ea senya.

E ka etsoa ka ho buoa ka ntle kapa ka laparoscopy (ho sebelisoa li-incision tse nyenyane le lisebelisoa tse khethehileng).

3. Phekolo ea mahlaseli: Phekolo ena e sebelisa mahlaseli a matla haholo ho bolaea lisele tsa kankere.

E ka fanoa ka ntle (ho tloha mochining o ka ntle ho'mele) kapa ka hare (ka li - implant tse behiloeng haufi le hlahala).

4. Phekolo ea lihormone: Phekolo ena e fokotsa lihormone tsa banna (li-androgen)'meleng, tse ka fokotsang kapa tsa emisa ho hōla ha kankere ea tšoelesa ea senya.

E ka sebelisoa e le mong kapa e kopane le mekhoa e meng ea phekolo.

5. Chemotherapy: Kalafo ena e sebelisa lithethefatsi ho bolaea lisele tsa kankere.

E ka sebelisoa bakeng sa kankere ea tšoelesa ea senya e tsoetseng pele e nametseng likarolong tse ling tsa'mele.

6. Ho phekola ka ho sebelisa matla a ho itšireletsa mafung: Phekolo ena e thusa tsamaiso ea'mele ea ho itšireletsa mafung ho loantša kankere.

E ka sebelisoa bakeng sa kankere ea tšoelesa ea senya e tsoetseng pele e sa kang ea arabela liphekolong tse ling.

7. Phekolo e lebisitsoeng: Phekolo ena e lebisa liphatsa tse itseng tsa lefutso kapa liprotheine tse thusang lisele tsa kankere hore li hōle le ho phela.

E ka sebelisoa bakeng sa kankere ea tšoelesa ea senya e tsoetseng pele e sa kang ea arabela liphekolong tse ling.

8. Cryotherapy: Kalafo ena e sebelisa serame se matla ho hoamisa le ho bolaea lisele tsa kankere.

E ka sebelisoa bakeng sa kankere ea tšoelesa ea senya e sa tsoa qala kapa bakeng sa kankere e khutlileng ka mor'a mekhoa e meng ea phekolo.

9. High-intensity focused ultrasound (HIFU): Kalafo ena e sebelisa maqhubu a molumo a phahameng ho futhumatsa le ho senya lisele tsa kankere.

E ka sebelisoa bakeng sa kankere ea tšoelesa ea senya e sa tsoa qala kapa bakeng sa kankere e khutlileng ka mor'a mekhoa e meng ea phekolo.

10. Ho leta ka hloko: Mokhoa ona o akarelletsa ho hlahloba kankere ka hloko ka ho e hlahloba le ho e hlahloba kamehla, empa ho sa qale phekolo ntle le haeba matšoao a hlaha kapa a fetoha.

E ka 'na ea e-ba e loketseng banna ba hōlileng ba nang le kankere ea tšoelesa ea senya e hōlang butle le ba nang le maemo a mang a tebileng a bophelo.

Ho bohlokoa ho buisana ka mekhoa eohle ea phekolo le sehlopha sa tlhokomelo ea bophelo ho fumana tsela e molemohali ea ho sebetsana le boemo ka bong.

['Litšupiso']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

['Tlhokomeliso: tsa bongaka']

["Websaete ena e etselitsoe ho ruta le ho fana ka boitsebiso feela'me ha e fane ka keletso ea bongaka kapa litšebeletso tsa litsebi."]

["Boitsebiso bo fanoeng ha boa lokela ho sebelisoa ho hlahloba kapa ho phekola bothata ba bophelo bo botle kapa lefu,'me ba batlang keletso ea bongaka ba lokela ho buisana le ngaka e nang le lengolo la tumello."]

['Ka kōpo hlokomela hore neural net e hlahisang likarabo lipotsong, ha e nepahale haholo-holo ha ho tluoa linomorong.']

["Kamehla batla keletso ea ngaka ea hao kapa mofani e mong ea tšoanelehang oa tlhokomelo ea bophelo mabapi le boemo ba bongaka. Le ka mohla u se ke ua hlokomoloha keletso ea setsebi sa bongaka kapa ua lieha ho e batla ka lebaka la ntho eo u e balileng websaeteng ena. Haeba u nahana hore u ka 'na ua ba le boemo ba tšohanyetso ba bongaka, letsetsa 911 kapa u ee kamoreng ea tšohanyetso e haufi hang-hang. Ha ho kamano ea ngaka le mokuli e bōptjoang ke websaeteng ena kapa tšebeliso ea eona. BioMedLib kapa basebetsi ba eona, kapa motho leha e le ofe ea tlatsetsang ho websaeteng ena, ha a etse litemoso, tse hlakileng kapa tse sa hlakang, mabapi le boitsebiso bo fanoeng mona kapa tšebeliso ea eona."]

['Tlhokomeliso: litokelo tsa bangoli']

['Molao oa Digital Millennium Copyright Act oa 1998, 17 U.S.C. § 512 (DMCA) o fana ka litokelo tsa beng ba litokelo tsa bangoli ba lumelang hore thepa e hlahang Inthaneteng e hatakela litokelo tsa bona tlasa molao oa litokelo tsa bangoli ba U.S. ']

['Haeba u lumela ka tumelo e ntle hore litaba leha e le life kapa thepa e fumanehang mabapi le websaeteng kapa litšebeletso tsa rona e tlōla litokelo tsa hau tsa molao, uena (kapa moemeli oa hau) a ka re romella tsebiso e kōpang hore litaba kapa thepa e tlosoe, kapa ho fihlella ho eona ho thibeloe. ']

['Ditsebiso di tlameha ho romelwa ka lengolo ka imeile (bona karolo ya "Ho iteanya" bakeng sa aterese ya imeile). ']

["DMCA e hloka hore tsebiso ea hao ea ho tlōla ha molao ho boleloang hore e na le boitsebiso bo latelang: (1) tlhaloso ea mosebetsi o sirelelitsoeng ka molao o boleloang hore o tlōloa; (2) tlhaloso ea litaba tse boleloang hore li tlōla molao le boitsebiso bo lekaneng ho re lumella ho fumana litaba; (3) boitsebiso ba ho ikopanya le uena, ho akarelletsa aterese ea hau, nomoro ea fono le aterese ea imeile; (4) polelo ea hau ea hore u na le tumelo e ntle ea hore litaba ka tsela e belaelloang ha e lumelloe ke mong'a litokelo tsa molao, kapa moemeli oa eona, kapa ka ts'ebetso ea molao leha e le ofe; "]

['(5) polelo e saennweng ke wena, tlasa kotlo ya ho hlapanya leshano, ya hore tlhahisoleseding e tsebisong e nepahetse le hore o na le matla a ho tiisa ditokelo tsa mongodi tseo ho thweng di a tlolwa; ']

["le (6) ho saena ka letsoho kapa ka elektronike ha mong'a litokelo tsa bangoli kapa motho ea lumeletsoeng ho nka khato lebitsong la mong'a litokelo tsa bangoli. "]

['Ho hloleha ho kenyelletsa tlhahisoleseding yohle e ka hodimo ho ka baka ho dieha ha ho sebetswa tletlebo ya hao.']

['Ho Iteanya']

['Ka kōpo re romelle imeile ka potso / tlhahiso leha e le efe.']

How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

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