Pathophysiology of colon cancer ngarujuk kana mékanisme jeung prosés nu ngabalukarkeun tumuwuhna jeung kamajuan kanker usus.
Kanker usus gedé, ogé katelah kanker kolorektal, nyaéta jenis kanker anu dimimitian dina usus gedé atawa rektum, anu mangrupa bagian tina peujit gedé.
Biasana, ieu téh tumuwuhna nu disebut polip, nu bisa jadi kanker.
Pathofisiologi kanker usus gedé ngalibatkeun sababaraha faktor, kaasup mutasi genetik, peradangan, jeung faktor lingkungan.
Mutasi génétik bisa lumangsung dina DNA sél usus, ngabalukarkeun tumuwuhna sél jeung babagi sél nu teu kakontrol.
Mutasi ieu bisa diwariskeun atawa diala, sarta bisa mangaruhan rupa-rupa gén nu aya patalina jeung tumuwuhna, ngabagi, jeung ngalereskeun sél.
Peradangan dina usus gedé, nu bisa disababkeun ku panyakit radang usus, ogé bisa nambahan résiko kanker usus gedé.
Peradangan kronis bisa ngabalukarkeun sékrési zat kimia nu ngagedékeun jeung ngabagi sél, nu bisa ngabalukarkeun kanker.
Faktor lingkungan, saperti kadaharan, gaya hirup, jeung kakeunaan bahan kimia nu tangtu, ogé bisa ngabalukarkeun kanker usus.
Misalna, lamun loba ngadahar daging beureum jeung daging olahan, bisa ngabalukarkeun kanker usus.
Faktor séjénna, saperti obesitas, ngaroko, jeung kurang aktipitas fisik, ogé bisa nambahan résiko.
Lamun geus aya kanker usus, éta bisa mekar ngaliwatan sababaraha tahap, ti mimiti kanker nu kakurung dina usus nepi ka tahap nu leuwih maju nu geus sumebar ka bagian awak séjénna.
Sél kanker bisa nyerang jaringan jeung organ nu deukeut, sarta bisa ogé sumebar ngaliwatan sistim limfatik atawa aliran getih ka tempat nu jauh, saperti ati atawa bayah.
Perawatan kanker usus gedé biasana ngalibatkeun kombinasi bedah, kémoterapi, jeung terapi radiasi, gumantung kana tahap jeung lokasi kanker.
Ngadeteksi jeung ngubaran kanker dina tahap awal téh penting pisan pikeun ngaronjatkeun hasilna, sabab kanker usus gedé bisa diubaran lamun dicekel dina tahap awal.
Pamariksaan nu rutin, saperti kolonoskopi, bisa ngabantu ngadeteksi kanker usus gedé dina tahap awalna, waktu éta bisa diubaran.
Vidal-Vanaclocha F: The liver prometastatic reaction of cancer patients: implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron. 2011, 4 (2): 163-80.
Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
['Bantahan: masalah médis']
['Situs wéb ieu ngan keur tujuan pendidikan jeung informasi, lain pikeun méré naséhat atawa jasa profésional.']
['Informasi nu disadiakeun di dieu teu kudu dipaké pikeun nangtukeun atawa ngubaran masalah kaséhatan atawa panyakit.']
['Punten perhatikeun yén jaringan saraf nu ngahasilkeun jawaban kana pananya, teu akurat lamun ngeunaan eusi numeris. contona, jumlah jalma nu didiagnosis kalawan panyakit husus.']
['Salawasna ménta naséhat ti dokter atawa panyadia kaséhatan nu mumpuni séjénna ngeunaan kaayaan médis. Ulah ngalalaworakeun naséhat médis profésional atawa nunda néangan éta kusabab hal nu geus maca dina ramatloka ieu. Lamun anjeun mikir anjeun bisa jadi boga kaayaan darurat médis, nelepon 911 atawa indit ka kamar darurat pangdeukeutna langsung.']
['Bantahan: hak cipta']
['Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (DMCA) nyadiakeun jalan pikeun nu boga hak cipta nu percaya yén bahan nu muncul di Internet ngalanggar hak-hakna dina hukum hak cipta AS. ']
['Lamun anjeun percaya yén aya eusi atawa bahan nu disadiakeun dina situs wéb atawa jasa urang ngalanggar hak cipta anjeun, anjeun (atawa agén anjeun) bisa ngirimkeun béwara ka kami pikeun nyuhunkeun eusi atawa bahan éta dipiceun, atawa aksés ka éta diblokir.']
['Bewara kudu dikirimkeun ku email (tempo bagian "Kontak" pikeun alamat email).']
['DMCA merlukeun yén bewara Anjeun tina ngalanggar hak cipta disangka kaasup informasi di handap ieu: (1) pedaran karya nu hak ciptana nu subyek ngalanggar ngaku; (2) pedaran eusi nu disangka ngalanggar jeung informasi cukup pikeun ngidinan urang pikeun nomeran eusi; (3) informasi kontak pikeun anjeun, kaasup alamat anjeun, nomer telepon jeung alamat surélék; (4) pernyataan ku anjeun nu boga kapercayaan alus iman nu eusi dina ragam complaining ngeunaan teu otorisasi ku nu boga hak cipta, atawa agén anak, atawa ku operasi hukum nu mana wae; ']
['(5) pernyataan nu ditandatanganan ku Sadérék, nu ngajamin yén informasi nu aya dina éta surat téh bener jeung Sadérék boga wewenang pikeun ngabéla hak cipta nu diklaim dilanggar.']
['jeung (6) tanda tangan nu nyata atawa éléktronik nu boga hak cipta atawa jalma nu boga wewenang pikeun ngawakilan nu boga hak cipta. ']
['Lamun teu kaasup kabéh informasi di luhur, bisa ngalambatkeun panalungtikan keluhan.']
['Kontak']
['Mangga kirimkeun email ka kami lamun aya pertanyaan/saran.']
What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
Disclaimer: medical
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.
The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.
Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.
Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.
Disclaimer: copyright
The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.
['Ngeunaan']
['BioMedLib ngagunakeun komputer otomatis (algoritma mesin-learning) pikeun ngahasilkeun pasangan pertanyaan-jawaban.']
['Urang mimitian ku 35 juta publikasi biomedis tina PubMed/Medline. ogé, kaca web tina RefinedWeb.']
