How to treat Prostate cancer?

['Reetsa tsebe eno']

Go ka alafiwa kankere ya kgeleswa ya setlha jang?

Go na le mefuta e le mmalwa ya kalafi e e ka dirisiwang go alafa kankere ya kgeleswa ya setlha, go ikaegile ka gore e mo kgatong efe le gore e masisi go le kana kang, le ka botsogo jwa molwetse ka kakaretso le gore o rata kalafi efe.

Kalafi e e tlwaelegileng e akaretsa:

1. Go nna o etse tlhoko: Mokgwa ono o akaretsa go nna o etse tlhoko kankere ka go nna o tlhatlhobiwa ka metlha le go dirwa diteko, go na le gore o simolole kalafi ka yone nako eo.

E ka nna ya tshwanela banna ba ba nang le kankere ya kgeleswa ya setlha e e kotsi thata.

2. Karo: Karo ya go ntsha kgeleswa ya setlha ke karo e mo go yone go ntshiwang kgeleswa ya setlha.

E ka dirwa ka karo e e bulegileng kgotsa ka laparoscopy (go dirisiwa dintho tse dinnye le didirisiwa tse di kgethegileng).

3. Kalafi ya marang: Kalafi eno e dirisa marang a a maatla thata go bolaya disele tsa kankere.

E ka tsenngwa mo mmeleng (ka motšhine o o kwa ntle ga mmele) kgotsa mo teng ga mmele (ka go tsenya sengwe gaufi le tlhagala).

Kalafi ya dihoromone: Kalafi eno e fokotsa selekanyo sa dihoromone tsa banna (androgens) mo mmeleng, tse di ka fokotsang kana tsa emisa go gola ga kankere ya kgeleswa ya setlha.

E ka dirisiwa e le nosi kgotsa e dirisiwa mmogo le mefuta e mengwe ya kalafi.

5. Kalafi ya dikhemikale: Kalafi eno e dirisa diokobatsi go bolaya disele tsa kankere.

E ka dirisiwa mo kankere ya kgeleswa ya setlha e e setseng e etegetse e e setseng e aname kwa dikarolong tse dingwe tsa mmele.

6. Kalafi ya go lwantsha malwetse: Kalafi eno e thusa thulaganyo ya mmele ya go lwantsha malwetse go lwantsha kankere.

E ka dirisiwa mo kankere ya kgeleswa ya setlha e e sa foleng e e sa arabeleng kalafi epe e nngwe.

Kalafi e e diretsweng go bolaya disele tsa kankere: Kalafi eno e tlhasela dijini kgotsa diporoteine tse di rileng tse di thusang disele tsa kankere go gola le go tshela.

E ka dirisiwa mo kankere ya kgeleswa ya setlha e e sa foleng e e sa arabeleng kalafi epe e nngwe.

8. Cryotherapy: Kalafi eno e dirisa serame se se feteletseng go gatsetsa le go bolaya disele tsa kankere.

E ka dirisiwa mo kankere ya kgeleswa ya setlha e e sa tswang go simolola kgotsa mo kankere e e boileng morago ga go alafiwa ka ditsela tse dingwe.

9. High-intensity focused ultrasound (HIFU): Kalafi eno e dirisa makhubu a modumo a a nang le maatla a magolo go gotetsa le go senya disele tsa kankere.

E ka dirisiwa mo kankere ya kgeleswa ya setlha e e sa tswang go simolola kgotsa mo kankere e e boileng morago ga go alafiwa ka ditsela tse dingwe.

10. Go leta ka kelotlhoko: Mokgwa ono o akaretsa go nna o etse tlhoko kankere ka go tlhatlhoba le go dira diteko ka metlha, mme o sa simolole kalafi kwantle ga fa matshwao a yone a bonala kgotsa a fetoga.

E ka nna ya tshwanela banna ba ba godileng ba ba nang le kankere ya kgeleswa ya setlha e e golang ka bonya le ba ba nang le mathata a mangwe a a masisi a botsogo.

Go botlhokwa gore o buisane le setlhopha sa kalafi ka mefuta yotlhe ya kalafi gore o tle o bone gore ke eng se se ka dirwang mo kgannyeng nngwe le nngwe.

['Ditshupiso']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

['Go se ikarabele: kalafi']

['Web site eno e diretswe go ruta le go naya tshedimosetso fela mme ga e neye kgakololo ya kalafi kgotsa ditirelo tsa seporofešenale.']

['Tshedimosetso e e neelwang ga e a tshwanela go dirisiwa go bona bolwetse kana go alafa bothata jwa botsogo, mme batho ba ba batlang kgakololo ya kalafi ba tshwanetse go ikgolaganya le ngaka e e nang le laesense.']

['Tsweetswee ela tlhoko gore thulaganyo ya methapo e e dirang dikarabo tsa dipotso tseno, ga e a tlhomama fa go tla mo dilong tsa dipalo. Ka sekai, palo ya batho ba ba nang le bolwetse bongwe jo bo rileng.']

['Ka metlha batla kgakololo ya ngaka ya gago kgotsa moabi yo mongwe wa kalafi yo o tshwanelegang malebana le boemo jwa kalafi. Le ka motlha o se ka wa itlhokomolosa kgakololo ya kalafi ya porofeshenale kgotsa wa diega go e batla ka ntlha ya sengwe se o se badileng mo website eno. Fa o akanya gore o ka tswa o na le boemo jwa tshoganyetso jwa kalafi, leletsa 911 kgotsa o ye kwa kamoreng ya tshoganyetso e e gaufi le wena ka bonako. Ga go na kamano epe ya ngaka le molwetse e e tlisiwang ke website eno kgotsa go e dirisa. BioMedLib kgotsa badiri ba yone, kgotsa ope fela yo o tsentseng letsogo mo website eno, ga ba dire ditshupetso dipe, tse di tlhamaletseng kgotsa tse di sa tlhamalalang, malebana le tshedimosetso e e mo go yone kgotsa go e dirisa.']

['Go ikgatholosa: ditshwanelo tsa bokwadi']

['Molao wa Digital Millennium Copyright wa 1998, 17 U.S.C. § 512 (the DMCA) o tlamela ka kgetse ya beng ba ditshwanelo ba ba dumelang gore matheriale o o tlhagelelang mo inthaneteng o gataka ditshwanelo tsa bona go ya ka molao wa ditshwanelo wa U.S.']

['Fa o dumela ka pelo yotlhe gore tshedimosetso kgotsa matheriale o o mo website ya rona kgotsa ditirelo tsa rona o gataka ditshwanelo tsa gago tsa semolao, wena (kgotsa moemedi wa gago) o ka re romelela kitsiso o kopa gore tshedimosetso eo kgotsa matheriale oo o tlosiwe kgotsa o thibelwe go o fitlhelela.']

['Dikitsiso di tshwanetse go romelwa ka go kwala ka imeili (leba karolo ya "Contact" go bona aterese ya imeili).']

['DMCA e batla gore kitsiso ya gago ya go tlolwa ga ditshwanelo tsa gago e akaretse tshedimosetso e e latelang: (1) tlhaloso ya tiro e e sireleditsweng ka ditshwanelo e go tweng e tlotswe; (2) tlhaloso ya diteng tse go tweng di tlotswe le tshedimosetso e e lekaneng go re letla go bona diteng; (3) tshedimosetso ya go ikgolaganya le wena, go akaretsa aterese ya gago, nomoro ya mogala le aterese ya imeile; (4) polelo ya gago ya gore o dumela ka pelo yotlhe gore diteng tse di tlotsweng ga di a letlelelwa ke mong wa ditshwanelo tsa gago, kgotsa moemedi wa gagwe, kgotsa ka molao ope; ']

['(5) polelo e e saenilweng ke wena, e e supang gore tshedimosetso e e mo kitsisong e boammaaruri le gore o na le thata ya go diragatsa ditshwanelo tsa botaki tse go tweng di gatakilwe;']

['le (6) saena ya mmatota kgotsa ya eleketeroniki ya mong wa tshwanelo ya go gatisa kgotsa motho yo o filweng tetla ya go dira mo boemong jwa mong wa tshwanelo ya go gatisa. ']

['Fa o sa akaretse tshedimosetso yotlhe e e fa godimo e ka nna ya diegisa go sekasekwa ga ngongorego ya gago.']

['Go Ikgolaganya']

['Tsweetswee re romelele imeile ka potso/kgakololo epe fela.']

How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

Disclaimer: medical

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