How is Lung cancer diagnosed?

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肺癌係點樣被診斷嘅呢?

肺癌係通過一系列嘅測試同手術嚟診斷嘅,包括:

1. 病史同身體檢查: 醫生會詢問你嘅症狀,吸煙史,同埋家族嘅肺癌史.

佢哋仲會做身體檢查,睇下有冇病徵.

2. 影像檢查:胸部X射線同埋電腦掃描 (CT) 通常用嚟做詳細嘅肺部同周圍嘅結構影像.

呢啲檢查可以幫助發現異常,例如腫瘤或結節,可能表明肺癌嘅存在.

3. 液細胞學: 喺顯微鏡下檢查液 (從肺部咳出嚟嘅粘液) 嚟搵癌細胞.

4. 活检: 摘取肺部组织样本,并在显微镜下检查,以确定是否存在癌细胞.

呢個可以係透過支氣管鏡,針生物檢查,或者手術生物檢查.

5. 支氣管檢查: 透過鼻子或者嘴巴 插入一個細嘅,有燈光嘅管道 通過喉去檢查呼吸道同肺部

呢個程序亦可以用嚟採取組織樣本,用嚟做生物檢查.

6. 細針吸收 (FNA): 一個細針被插入肺結節或腫瘤中,收集一個細胞樣本進行檢查.

7. 肺部切開: 用針去取肺部同胸部之間嘅液體,然後檢查是否有癌細胞.

8. 血液檢查: 雖然血液檢查本身唔能夠診斷肺癌, 但可以幫助確定病人嘅整體健康狀況, 同埋發現任何可能表明癌症嘅異常.

9. 骨掃描,核磁共振,寵物掃描,同埋其他檢查: 呢啲檢查可以用嚟判斷癌症是否已經擴散到身體其他部位.

一旦肺癌被診斷出,可能會進行額外嘅測試,嚟確定癌症嘅階段, 幫助決定治療方法.

呢啲測試可能包括更多嘅影像測試,例如腦部嘅CT掃描,骨頭掃描,或者陽子放射断層掃描 (PET).

參考資料

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Zhou P, Lu F, Wang J, Wang K, Liu B, Li N, Tang B: A portable point-of-care testing system to diagnose lung cancer through the detection of exosomal miRNA in urine and saliva. Chem Commun (Camb). 2020, 56 (63): 8968-8971.

Ni J, Guo Z, Zhang L: [The diagnostic significance of single or combination lung cancer-related serum biomarkers in high risk lung cancer patients]. Zhonghua Nei Ke Za Zhi. 2016, 55 (1): 25-30.

Nishiyama N, Nakatani S, Iwasa R, Taguchi S, Inoue K, Kinoshita H: [Differential diagnosis between peripheral lung cancer invading the chest wall and chest-wall tumors]. Kyobu Geka. 1997, 50 (10): 893-7.

Kang C, Wang D, Zhang X, Wang L, Wang F, Chen J: Construction and Validation of a Lung Cancer Diagnostic Model Based on 6-Gene Methylation Frequency in Blood, Clinical Features, and Serum Tumor Markers. Comput Math Methods Med. 2021, 2021 (): 9987067.

Heydari F, Rafsanjani MK: A Review on Lung Cancer Diagnosis Using Data Mining Algorithms. Curr Med Imaging. 2021, 17 (1): 16-26.

Li L, Feng T, Zhang W, Gao S, Wang R, Lv W, Zhu T, Yu H, Qian B: MicroRNA Biomarker hsa-miR-195-5p for Detecting the Risk of Lung Cancer. Int J Genomics. 2020, 2020 (): 7415909.

Li B, Yuan Q, Zou YT, Su T, Lin Q, Zhang YQ, Shi WQ, Liang RB, Ge QM, Li QY, Shao Y: CA-125, CA-153, and CYFRA21-1 as clinical indicators in male lung cancer with ocular metastasis. J Cancer. 2020, 11 (10): 2730-2736.

Magee ND, Villaumie JS, Marple ET, Ennis M, Elborn JS, McGarvey JJ: Ex vivo diagnosis of lung cancer using a Raman miniprobe. J Phys Chem B. 2009, 113 (23): 8137-41.

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How is lung cancer diagnosed?

Lung cancer is diagnosed through a combination of tests and procedures, which may include:

1. Medical history and physical examination: The doctor will ask about your symptoms, smoking history, and family history of lung cancer.

They will also perform a physical examination to check for any signs of the disease.

2. Imaging tests: Chest X-rays and computed tomography (CT) scans are commonly used to create detailed images of the lungs and surrounding structures.

These tests can help detect abnormalities, such as tumors or nodules, that may indicate the presence of lung cancer.

3. Sputum cytology: A sample of your sputum (mucus coughed up from the lungs) is examined under a microscope to look for cancer cells.

4. Biopsy: A sample of lung tissue is removed and examined under a microscope to determine if cancer cells are present.

This can be done through a bronchoscopy, needle biopsy, or surgical biopsy.

5. Bronchoscopy: A thin, lighted tube with a camera is inserted through the nose or mouth and down the throat to examine the airways and lungs.

This procedure can also be used to collect tissue samples for biopsy.

6. Fine-needle aspiration (FNA): A thin needle is inserted into the lung nodule or mass to collect a sample of cells for examination.

7. Thoracentesis: Fluid is removed from the space between the lungs and chest wall using a needle, and the fluid is then examined for cancer cells.

8. Blood tests: While blood tests alone cannot diagnose lung cancer, they can help determine the overall health of the patient and identify any abnormalities that may indicate the presence of cancer.

9. Bone scan, mri, pet scan, and other tests: These tests may be used to determine if the cancer has spread to other parts of the body.

Once lung cancer is diagnosed, additional tests may be performed to determine the stage of the cancer, which helps guide treatment decisions.

These tests may include more imaging tests, such as a CT scan of the brain, bone scan, or positron emission tomography (PET) scan.

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