What causes Prostate cancer?

['Pirengang kaca puniki']

Napi sane ngawinang kanker prostat?

Sane ngawinang kanker prostat nenten kauningin, sakewanten sampun katentuang makudang faktor sane prasida nincapang baya nglimbakang penyakit.

Puniki taler:

1. Umur: Risiko kanker prostat sayan nincap nganutin yusa, katahnyané ring anak lanang sané sampun mayusa 65 warsa.

2. Sejarah kulawarga: Anak lanang sane madue riwayat kanker prostat ring kulawarga, utaminnyane aji utawi nyama lanang sane keni penyakit punika, wenten ring risiko sane tegeh.

3. Ras: Pria Afrika Amerika madué risiko sané ageng ngamolihang kanker prostat bandingang sareng pria ras tiosan.

4. Diet: Diet sane akeh lemak, utamanyane lemak buron, prasida nincapang risiko kanker prostat.

5. Obesitas: Kalemenan utawi obesitas prasida nincapang risiko ngamolihang kanker prostat.

6. Hormon: Kadar testosteron miwah hormon lanang sane tegeh prasida nincapang baya kanker prostat.

7. Peradangan: Peradangan prostat kronis, sekadi prostatitis, prasida nincapang baya kanker prostat.

8. Genetika: Mutasi genetik sane katami, sekadi ring gen BRCA1 miwah BRCA2, prasida nincapang risiko kanker prostat.

Penting pisan mangda uning indik madué asiki utawi akéh faktor risiko puniki nénten ja mateges anak lanang pastika pacang keni kanker prostat, taler akéh anak lanang sané keni kanker prostat nénten madué faktor risiko sané kauningin.

Tiosan punika, penelitian kantun mamargi mangda prasida ngresepang sane ngawinang kanker prostat miwah ngidentifikasi faktor risiko tambahan.

['Rujukan']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Riihimäki M, Thomsen H, Brandt A, Sundquist J, Hemminki K: What do prostate cancer patients die of? Oncologist. 2011, 16 (2): 175-81.

Gilligan T: Social disparities and prostate cancer: mapping the gaps in our knowledge. Cancer Causes Control. 2005, 16 (1): 45-53.

Newschaffer CJ, Otani K, McDonald MK, Penberthy LT: Causes of death in elderly prostate cancer patients and in a comparison nonprostate cancer cohort. J Natl Cancer Inst. 2000, 92 (8): 613-21.

Frydenberg M, Wijesinha S: Diagnosing prostate cancer - what GPs need to know. Aust Fam Physician. 2007, 36 (5): 345-7.

Shimodaira K, Nakashima J, Nakagami Y, Hirasawa Y, Hashimoto T, Satake N, Gondo T, Namiki K, Ohori M, Ohno Y: Prognostic Value of Platelet Counts in Patients with Metastatic Prostate Cancer Treated with Endocrine Therapy. Urol J. 2020, 17 (1): 42-49.

Martínez-Salamanca JI, Ballesteros CM, Carballido Rodríguez J: [Epidemiological fundamentals of clinically localized prostate cancer]. Arch Esp Urol. 2011, 64 (8): 703-10.

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What causes prostate cancer?

The exact cause of prostate cancer is not known, but several factors have been identified that may increase the risk of developing the disease.

These include:

1. Age: The risk of prostate cancer increases with age, with most cases occurring in men over the age of 65.

2. Family history: Men with a family history of prostate cancer, particularly a father or brother with the disease, are at a higher risk.

3. Race: African American men have a higher risk of developing prostate cancer than men of other races.

4. Diet: A diet high in fat, particularly animal fat, may increase the risk of prostate cancer.

5. Obesity: Being overweight or obese may increase the risk of developing prostate cancer.

6. Hormones: High levels of testosterone and other male hormones may increase the risk of prostate cancer.

7. Inflammation: Chronic inflammation of the prostate, such as prostatitis, may increase the risk of prostate cancer.

8. Genetics: Certain inherited genetic mutations, such as those in the BRCA1 and BRCA2 genes, may increase the risk of prostate cancer.

It is important to note that having one or more of these risk factors does not mean that a man will definitely develop prostate cancer, and many men with prostate cancer have no known risk factors.

Additionally, research is ongoing to better understand the causes of prostate cancer and identify additional risk factors.

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