Adda sumagmamano a pagpilian iti panangagas iti kanser ti prostate, depende iti kasasaad ken kinagrabe ti kanser, agraman ti salun-at ken personal a kayat ti pasiente.
Dadduma a gagangay a panangagas iramanna:
1. Aktibo a panangbantay: Daytoy a pamay-an ramanenna ti nainget a panangbantay iti kanser babaen ti regular a panangeksamen ken panangeksamen, imbes a dagus a mangrugi iti panangagas.
Mabalin a maitutop dayta kadagiti lallaki a bassit ti risgoda nga agkanser iti prostate.
2. Operasion: Ti prostatectomy ket maysa a pamay-an ti operasion a mangikkat iti prostate gland.
Mabalin nga aramiden dayta babaen ti open surgery wenno laparoscopically (mangusar kadagiti babassit a sugat ken espesial nga alikamen).
3. Radiation therapy: Daytoy a panangagas ket agusar iti napigsa a radiasion a mangpatay kadagiti selula ti kanser.
Mabalin a maited dayta iti ruar (manipud iti makina nga adda iti ruar ti bagi) wenno iti uneg (babaen kadagiti implant a naikabil iti asideg ti tumor).
4. Hormone therapy: Daytoy a panangagas kissayanna ti kaadu dagiti hormone ti lalaki (androgen) iti bagi, a mangpabannayat wenno mangpasardeng iti idadakkel ti kanser ti prostate.
Mabalin a maymaysa wenno mausar a kadua ti dadduma a panangagas.
5. Chemotherapy: Daytoy a panangagas agusar kadagiti agas a mangpapatay kadagiti selula ti kanser.
Mabalin a mausar dayta iti kanser ti prostate a nagsaknapen iti dadduma a paset ti bagi.
6. Immunotherapy: Daytoy a panangagas tulonganna ti resistensia a manglaban iti kanser.
Mabalin nga usaren dayta iti kanser ti prostate a saan a nagresponde iti dadduma a panangagas.
7. Targeted therapy: Daytoy a panangagas ti mangiturong kadagiti espesipiko a gene wenno protina a tumulong kadagiti selula ti kanser a dumakkel ken agbiag.
Mabalin nga usaren dayta iti kanser ti prostate a saan a nagresponde iti dadduma a panangagas.
8. Cryotherapy: Daytoy a panangagas agusar iti nakaro a lamiis tapno palamiisen ken papatayen dagiti selula ti kanser.
Mabalin a mausar dayta iti nasapa a kanser ti prostate wenno iti kanser a nagsubli kalpasan ti dadduma a panangagas.
9. High-intensity focused ultrasound (HIFU): Daytoy a panangagas ket agusar kadagiti high-frequency sound waves tapno papudoten ken dadaelenna dagiti selula ti kanser.
Mabalin a mausar dayta iti nasapa a kanser ti prostate wenno iti kanser a nagsubli kalpasan ti dadduma a panangagas.
10. Panaguray a siaannad: Daytoy a pamay-an ramanenna ti nainget a panangmonitor iti kanser babaen ti regular a panangeksamen ken panangeksamen, ngem saan a panangirugi iti panangagas malaksid no agparang wenno agbalbaliw dagiti sintoma.
Mabalin a maitutop dayta kadagiti lallakay ken babbaket nga addaan iti nabannayat nga umadu a kanser ti prostate ken dadduma pay a nakaro a sakit.
Napateg a pagsasaritaan ti amin a pagpilian ti panangagas iti maysa a grupo ti mangay-aywan iti salun-at tapno maikeddeng ti kasayaatan a pamay-an ti panangagas iti tunggal indibidual a kaso.
Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.
Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.
Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.
Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.
Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.
de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.
Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.
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How to treat prostate cancer?
There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.
Some common treatments include:
1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.
It may be suitable for men with low-risk prostate cancer.
2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.
It can be done through open surgery or laparoscopically (using small incisions and specialized tools).
3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.
It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).
4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.
It can be used alone or in combination with other treatments.
5. Chemotherapy: This treatment uses drugs to kill cancer cells.
It may be used for advanced prostate cancer that has spread to other parts of the body.
6. Immunotherapy: This treatment helps the immune system fight cancer.
It may be used for advanced prostate cancer that has not responded to other treatments.
7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.
It may be used for advanced prostate cancer that has not responded to other treatments.
8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.
It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.
It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.
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