What causes Prostate cancer?

['Denggem daytoy a panid']

Ania ti pakaigapuan ti kanser iti prostate?

Saan nga ammo ti eksakto a pakaigapuan ti kanser ti prostate, ngem nailasin ti sumagmamano a banag a mabalin a mangpakaro iti peggad a maaddaan iti dayta a sakit.

Dagitoy ti pakairamanan:

1. Edad: Umad-adu ti agsakit iti kanser ti prostate bayat nga agmataengan ti maysa, a kaaduan a lallaki nga agsakit iti dayta ket agtawen iti nasurok a 65.

2. Pakasaritaan ti pamilia: Dagiti lallaki nga addaan iti pakasaritaan ti pamilia iti kanser ti prostate, nangruna ti ama wenno kabsat a lalaki nga addaan iti sakit, ket ad-adda a maaddaan iti dayta.

3. Rasa: Dagiti Africano nga Americano a lallaki ad-adda a maaddaan iti kanser ti prostate ngem kadagiti lallaki iti dadduma a rasa.

4. Taraon: Ti taraon a nabaknang iti taba, nangruna iti taba ti animal, mabalin a mangpadakkel iti peggad ti kanser ti prostate.

5. Panagpalukmeg: Ti sobra a kinalukmeg wenno kinalukmeg mabalin a mangpaadu iti peggad ti panagsakit iti kanser ti prostate.

6. Hormones: Dagiti nangato a testosterone ken dadduma pay a hormone ti lalaki mabalin a mangpadakkel iti peggad ti kanser ti prostate.

7. Pannaka-inflammation: Ti napaut a pannaka-inflammation ti prostate, kas iti prostatitis, mabalin a mangpakaro iti peggad ti kanser ti prostate.

8. Genetics: Dadduma a natawid a genetic mutation, kas kadagidiay adda kadagiti gene a BRCA1 ken BRCA2, mabalin a mangpadakkel iti peggad ti kanser ti prostate.

Napateg a laglagipen a ti kaadda ti maysa wenno ad-adu pay kadagitoy a pakaigapuan ti panagsakit dina kaipapanan a sigurado nga agsakit ti maysa a lalaki iti kanser ti prostate, ken adu a lallaki nga addaan iti kanser ti prostate ti awan ti naammuan a pakaigapuan ti panagsakit.

Kanayonanna, agtultuloy ti panagsirarak tapno ad-adda a maawatan dagiti pakaigapuan ti kanser ti prostate ken maammuan dagiti kanayonan a pakaigapuan ti panagsakit.

['Dagiti reperensia']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Riihimäki M, Thomsen H, Brandt A, Sundquist J, Hemminki K: What do prostate cancer patients die of? Oncologist. 2011, 16 (2): 175-81.

Gilligan T: Social disparities and prostate cancer: mapping the gaps in our knowledge. Cancer Causes Control. 2005, 16 (1): 45-53.

Newschaffer CJ, Otani K, McDonald MK, Penberthy LT: Causes of death in elderly prostate cancer patients and in a comparison nonprostate cancer cohort. J Natl Cancer Inst. 2000, 92 (8): 613-21.

Frydenberg M, Wijesinha S: Diagnosing prostate cancer - what GPs need to know. Aust Fam Physician. 2007, 36 (5): 345-7.

Shimodaira K, Nakashima J, Nakagami Y, Hirasawa Y, Hashimoto T, Satake N, Gondo T, Namiki K, Ohori M, Ohno Y: Prognostic Value of Platelet Counts in Patients with Metastatic Prostate Cancer Treated with Endocrine Therapy. Urol J. 2020, 17 (1): 42-49.

Martínez-Salamanca JI, Ballesteros CM, Carballido Rodríguez J: [Epidemiological fundamentals of clinically localized prostate cancer]. Arch Esp Urol. 2011, 64 (8): 703-10.

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What causes prostate cancer?

The exact cause of prostate cancer is not known, but several factors have been identified that may increase the risk of developing the disease.

These include:

1. Age: The risk of prostate cancer increases with age, with most cases occurring in men over the age of 65.

2. Family history: Men with a family history of prostate cancer, particularly a father or brother with the disease, are at a higher risk.

3. Race: African American men have a higher risk of developing prostate cancer than men of other races.

4. Diet: A diet high in fat, particularly animal fat, may increase the risk of prostate cancer.

5. Obesity: Being overweight or obese may increase the risk of developing prostate cancer.

6. Hormones: High levels of testosterone and other male hormones may increase the risk of prostate cancer.

7. Inflammation: Chronic inflammation of the prostate, such as prostatitis, may increase the risk of prostate cancer.

8. Genetics: Certain inherited genetic mutations, such as those in the BRCA1 and BRCA2 genes, may increase the risk of prostate cancer.

It is important to note that having one or more of these risk factors does not mean that a man will definitely develop prostate cancer, and many men with prostate cancer have no known risk factors.

Additionally, research is ongoing to better understand the causes of prostate cancer and identify additional risk factors.

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