How to treat Urticaria?

['Thikĩrĩria karatathi gaka']

Ũngĩhiũrania na mũrimũ ũcio atĩa?

Mũrimũ wa ironda cia mahũri, ũrĩa kaingĩ wĩtagwo na rĩĩtwa rĩngĩ, nĩ mũrimũ wa ngothi ũrĩa wonanagio nĩ ironda iratherema na iratema, iria cingĩoneka mwĩrĩinĩ.

No ũkorũo ũrehagwo nĩ maũndũ matiganĩte, ta kũhiũha kũhiũha kũhiũha kũhiũha kũhiũha kũhiũha kũhiũha kũhiũha kũhiũha kũhiũha kũhiũha, mĩrimũ, kana mathĩna mangĩ ma mwĩrĩ.

Ũrigiti wa mũrimũ ũcio wĩhocetie harĩ ũrĩa ũigana na kĩrĩa kĩũreheire.

Maya nĩ mamwe ma njĩra iria kaingĩ ũrigitani ũngĩhũthĩrũo:

1. Ndawa cia kũhũrana na mahũha ma mwĩrĩ: Ndawa icio nĩ iteithagia kũniina rwagĩ na kũimba na njĩra ya kũgirĩrĩria histamine, ĩrĩa ĩrutagwo nĩ mwĩrĩ rĩrĩa mũndũ araigua ũũru.

Ndawa cia kũhũrana na mũrimũ ta diphenhydramine (Benadryl) kana loratadine (Claritin) no iteithie mũno mũndũ ũrũarĩte mũrimũ ũcio na njĩra hũthũ.

Arĩa marĩ na mũrimũ ũcio mũno, ndagĩtarĩ no ameere manyue ndawa irĩ na hinya cia kũhũrana na marũrũ.

2. Corticosteroids: Harĩa ndawa cia kũhũrana na marũngo itahotete, no ĩhũthĩrũo kũhũrana na kũimba na kũgirĩrĩria mwĩrĩ ndũkarũe.

Ndawa icio kaingĩ nĩ ciĩkagĩrũo kanua na no iteithie mũndũ na ihenya.

3. Ndawa cia kũhũrana na mũrimũ: Arĩa marĩ na mũrimũ wa kũgũmara mategũkoma na ndawa ingĩ, no maheo ndawa cia kũhũrana na mũrimũ ta cyclosporine kana methotrexate nĩguo mahũthĩre hinya wa mwĩrĩ kũhũrana na mũrimũ ũcio na kũnyihia kũimba.

4. Omalizumab: Ndawa ĩno nĩ monoclonal antibody ĩria ĩnyuagwo na ĩkahinga na kũgiria ĩthondeketwo na proteins ĩtagwo immunoglobulin E (IgE), ĩrĩa ĩnyitanagĩra na ũrĩa mũndũ aiguaga rĩrĩa arwara.

Njĩra ĩmwe ĩrĩa ĩhũthagĩrũo nĩ kũhonia mũrimũ wa mahũha marĩa matanyitagwo na njĩra ingĩ.

5. Gwĩthema maũndũ marĩa mangĩtũma mũndũ anyitwo nĩ mũrimũ ũcio: Kũmenya na gwĩthema maũndũ marĩa mangĩtũma mũndũ anyitwo nĩ mũrimũ ũcio no gũteithie kũgirĩrĩria ũthereme.

Maũndũ marĩa kaingĩ marehaga mĩrimũ ta irio, ndawa, kũrũrwo nĩ tũtambi, ũrugarĩ, heho, kana riũa.

6. Kũhihĩra mũndũ kĩndũ heho: Kũhihĩra mũndũ kĩndũ heho handũ harĩa ũraigua ruo no kũgirie kũigua ruo na kũimba.

7. Kũhumba: Kũhumba no kũhũthahũthĩrũo kũhooreria kũigua ruo na kũhũnia mũrimũ.

Mũndũ ahumbaga harĩa harĩ na thĩna ũcio gatambaya karĩ na maĩ, agacoka akaigĩrĩra gatambaya kangĩ igũrũ nĩguo ndakahutie.

8. Njĩra ya ũtheri: Ũtheri wa ultraviolet no ũteithie kũniina hinya wa mwĩrĩ wa kũrũa na mĩrimũ na kũhũnia mũrimũ ũcio.

Nĩ wega kwaranĩria na ndagĩtarĩ nĩguo agũtaarĩrie na njĩra ĩrĩa yagĩrĩire.

No magũteithie kũmenya kĩrĩa kĩratũma ũnyite kaimana na magũtaarĩrie njĩra ĩrĩa wagĩrĩirũo nĩ kũhũthĩra.

['Ũhoro wa kwambĩrĩria']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Deleanu D, Nedelea I, Petricau C, Leru P, Dumitrascu D, Muntean A: Clinical impact of omalizumab in refractory chronic urticaria: One centre experience. Exp Ther Med. 2019, 18 (6): 5078-5081.

Grundmann SA, Kiefer S, Luger TA, Brehler R: Delayed pressure urticaria - dapsone heading for first-line therapy? J Dtsch Dermatol Ges. 2011, 9 (11): 908-12.

Staumont-Sallé D, Piette F, Delaporte E: [Etiological diagnosis and treatment of chronic urticaria]. Rev Med Interne. 2003, 24 (1): 34-44.

Akashi R, Ishiguro N, Shimizu S, Kawashima M: Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori. J Dermatol. 2011, 38 (8): 761-6.

Calogiuri G, Nettis E, Mandurino-Mirizzi A, Di Leo E, Macchia L, Foti C, Vacca A, Kounis NG: Omalizumab for the Treatment of Persistent Drug Induced Urticaria Elicited by Thienopyridines: A Case Report. Antiinflamm Antiallergy Agents Med Chem. 2020, 19 (3): 335-339.

['Ũkaana: thibitarĩ']

['Website ĩno ĩkoragwo ĩrĩ ya kũrutana na kũheana ũhoro tu na ti ya kũheana ũtaaro wa ũrigitani kana ũtungata wa kĩĩmwĩrĩ.']

['Ũhoro ũrĩa ũrĩ thĩinĩ wa broshua ĩyo ndwagĩrĩirũo kũhũthĩrũo gũthima kana kũrigita mũrimũ mũna, na arĩa marenda ũtaaro wa ũrigitani magĩrĩirũo gũcaria ũteithio wa ndagĩtarĩ.']

['No wone atĩ netiwaki ya neuron ĩrĩa ĩheanaga macokio ma ciũria icio, ndĩkoragwo na ũkinyanĩru mũno ũhoro-inĩ wĩgiĩ namba. Kwa ngerekano, mũigana wa andũ arĩa magwatĩtio mũrimũ mũna.']

['Hingo ciothe caria ũtaaro wa ndagĩtarĩ kana mũndũ ũngĩ wagĩrĩire ũgima-inĩ waku wa mwĩrĩ igũrũ rĩgiĩ mũrimũ. Ndũkaanahũthie ũtaaro wa ndagĩtarĩ kana ũcererũo kũũcaria nĩ ũndũ wa ũndũ ũthomete thĩinĩ wa website ĩno. Ũngĩkorũo ũrona ta wacemania na ũndũ mũhiũ, hũra thimũ 911 kana ũthiĩ thibitarĩ ya hakuhĩ na harĩa ũrĩ. Gũtirĩ ũrata wa ndagĩtarĩ na mũrwaru wonekaga nĩ ũndũ wa website ĩno kana kũhũthĩrũo kwayo. BioMedLib kana aruti ayo a wĩra, kana mũndũ ũngĩ wothe ũrutĩte wĩra thĩinĩ wa website ĩno, ndarĩ na ũira, wa ĩmwe kwa ĩmwe kana wa ĩmwe kwa ĩmwe, wĩgiĩ ũhoro ũrĩa ũheanĩtwo ho kana ũrĩa ũhũthĩrĩtwo.']

['Ũregani: wĩyathi wa kwandĩka']

['Watho wa Digital Millennium Copyright Act wa 1998, 17 U.S.C. § 512 (the DMCA) ũheanaga ũhoti wa ene a ihoto cia wandĩki arĩa metĩkĩtie atĩ ũhoro ũrĩa ũroneka intanetiinĩ nĩ ũtharĩtie ihooto ciao kũringana na watho wa U.S. wa ihoto cia wandĩki.']

['Ũngĩkorũo na wĩtĩkio atĩ ũhoro kana kĩndũ kĩna gĩtahingũrĩtwo ũhoro-inĩ wĩgiĩ website kana ũtungata witũ nĩ gĩgũthũkia ihooto ciaku, wee (kana mũndũ ũrĩa ũgũgũthondekera) no ũtũtũmĩre notithi ũkĩũria ũhoro kana kĩndũ kĩu kĩeherio, kana ũrigĩrĩrio ndũgacihũthĩre.']

["Marũa macio magĩrĩire gũtũmwo na njĩra ya kwandĩkwo na e-mail (rora ũhoro wa andirethi gĩcunjĩinĩ kĩa 'Maũndũ ma kwaranĩria')."]

['DMCA ĩbataraga atĩ notithi yaku ya kuuna ihooto cia wandĩki ĩkorwo na ũhoro ũyũ: (1) ũtaarĩria wa wĩra ũrĩa ũrĩ na ihooto cia wandĩki ũrĩa ũrarumwo; (2) ũtaarĩria wa ũhoro ũrĩa ũrarumwo na ũhoro mũiganu wa gũtũhotithia kũmenya kũrĩa ũhoro ũcio ũrĩ; (3) ũhoro waku wa kwaranĩria, hamwe na andirethi, namba ya thimũ na andirethi ya e-mail; (4) ndũmĩrĩri yaku atĩ wĩ na wĩtĩkio mwega atĩ ũhoro ũcio ũramenererio ndũrĩ na rũtha rwa mwene wa watho, kana mũrũgamĩrĩri, kana rwa watho o wothe; ']

['(5) nĩ mwandĩkanĩire, na nĩ mũkũheo mũkaana wa kũheenania, atĩ ũhoro ũrĩa ũrĩ kĩmenyithiainĩ kĩu nĩ wa ma na atĩ mũrĩ na ũhoti wa kũhingia ihooto iria mũreganĩte nacio;']

['na (6) kĩrore kĩa mwene kĩhoto kana kĩa mũndũ wĩtĩkĩritio gwĩtongoria handũ ha mwene kĩhoto.']

['Kwaga kwandĩka ũhoro ũcio wothe no gũtũme gũtangĩka gwaku kũhĩtũke.']

['Ũhoro wa Kwaranĩria']

['Tũma ndũmĩrĩri ya kũbucia kũgerera thimũ kana thimũ ya mohoro.']

How to treat urticaria?

Urticaria, commonly known as hives, is a skin condition characterized by itchy, raised welts that can appear on any part of the body.

It can be caused by various factors, including allergic reactions, infections, or underlying medical conditions.

Treatment for urticaria depends on the severity of the condition and the underlying cause.

Here are some common treatment options:

1. Antihistamines: These medications help to reduce itching and swelling by blocking the effects of histamine, a chemical released by the body during an allergic reaction.

Over-the-counter antihistamines such as diphenhydramine (Benadryl) or loratadine (Claritin) can be effective in mild cases.

In more severe cases, a doctor may prescribe stronger antihistamines.

2. Corticosteroids: In cases where antihistamines are not effective, corticosteroids such as prednisone may be prescribed to reduce inflammation and suppress the immune system.

These medications are usually taken orally and can provide quick relief.

3. Immunosuppressants: In cases of chronic urticaria that do not respond to other treatments, immunosuppressant drugs such as cyclosporine or methotrexate may be prescribed to suppress the immune system and reduce inflammation.

4. Omalizumab: This medication is an injectable monoclonal antibody that targets and blocks immunoglobulin E (IgE), a protein involved in allergic reactions.

It is typically used for chronic urticaria that does not respond to other treatments.

5. Avoid triggers: Identifying and avoiding triggers that cause urticaria can help prevent outbreaks.

Common triggers include certain foods, medications, insect bites, and exposure to heat, cold, or sunlight.

6. Cold compress: Applying a cold compress to the affected area can help reduce itching and swelling.

7. Wet wraps: Wet wraps can be used to soothe itching and reduce inflammation.

A damp cloth is wrapped around the affected area, and then a dry cloth is placed over it to retain moisture.

8. Phototherapy: Exposure to ultraviolet light can help suppress the immune system and reduce inflammation in some cases of chronic urticaria.

It is important to consult a healthcare professional for proper diagnosis and treatment of urticaria.

They can help determine the underlying cause and recommend the most appropriate treatment plan.

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