What are the risk factors for Alzheimer?

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阿爾茨海默氏症嘅風險因素係咩?

阿茲海默症有幾種風險因素,包括:

1. 年齡:隨著年齡增長,患阿茲海默症嘅風險會增加,大多數人喺 65 歲之後就會被診斷.

2. 遺傳學: 有阿茲海默症嘅家族史 或者有特定嘅基因,例如 APOE-e4 基因, 可以增加患呢個病嘅風險.

3. 頭部受傷: 頭部嚴重創傷或者多次腦震 可能會增加阿尔茨海默病嘅風險.

4. 心血管健康: 影響心臟同血管嘅疾病,例如高血壓,高膽固醇,糖尿病同肥胖, 都可以增加阿尔茨海默病嘅風險.

5. 生活方式嘅因素: 吸煙,過度飲酒,缺乏運動 都可以增加阿尔茨海默氏症嘅風險.

6. 認知不活躍: 缺乏精神刺激同教育水平低下 可能會增加阿尔茨海默氏症嘅風險.

7. 睡眠障礙: 睡眠障礙,例如睡眠呼吸暫停,可能會增加阿尔茨海默病嘅風險.

8. 心理因素: 抑鬱,壓力,同社會隔離 可能會增加阿尔茨海默氏症嘅風險.

值得注意嘅係,如果一個人有其中一個或以上嘅風險因子, 咁就唔代表佢會患上阿爾茨海默氏症, 而有啲人如果冇已知嘅風險因子, 可能仍然會患上呢個病.

但係,了解呢啲風險因素 可以幫到個人減少風險 同埋增進大腦健康

參考資料

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

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What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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