What are the risk factors for Breast cancer?

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乳腺癌嘅風險因子係咩?

乳腺癌有幾種風險因素 有啲係可以改變嘅,有啲係唔可以改變嘅

以下係最常見嘅風險因子:

1. 年齡: 乳腺癌嘅風險隨著年齡增長而增加,大多數病例喺 50 歲以上嘅女性發生.

2. 家庭史: 如果有近親嘅親戚,例如母親,妹妹,或者女兒,有乳腺癌, 你嘅風險會增加.

3. 基因突變: 一啲遺傳性基因突變,例如 BRCA1 同 BRCA2, 增加患乳腺癌嘅風險.

4. 生殖史: 早期初潮 (月經開始),晚期更年期,冇孩子或者喺 30 歲之後生第一個仔女 都可以增加呢個風險.

5. 荷爾蒙替代治療:經過更年期後長期使用雌激素同孕激素合併嘅荷爾蒙治療可以增加風險.

6. 飲酒: 飲酒會增加乳腺癌嘅風險.

7. 肥胖:超重或者肥胖會增加風險, 尤其喺更年期之後.

8. 身體活動: 缺乏身體活動可以增加風險.

9. 輻射: exposure to high doses of radiation, especially during childhood, can increase the risk. 辐射暴露,特別喺童年,可以增加風險.

10. 乳房密度: 乳房密度高嘅女性患乳腺癌嘅風險更高.

11. 月經史: 喺 12 歲之前開始月經嘅女性 或者喺 55 歲之後過咗更年期嘅女性 患上呢個病嘅風險略高

12. 哺乳期:從來冇哺乳過嘅女性 患乳腺癌嘅風險略高.

值得注意嘅係,有一個或多個風險因素並唔代表一個人一定會患上乳腺癌, 而冇任何風險因素並唔保證一個人唔會患上乳腺癌.

但係,了解呢啲風險因素 可以幫到個人對自己健康作出明智嘅決定 同埋減少風險

參考資料

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wung SF, Hepworth JT, Sparenga D, Merkle CJ: Cardiovascular Disease Risk and Breast Cancer Outcomes: A Pilot Study. Oncol Nurs Forum. 2015, 42 (5): E330-8.

Frankl G: Risk factors in breast cancer: are they important, are they the same in pre- and post-menopausal breast cancer patients? Oncology. 1980, 37 (1): 41-5.

Ho PJ, Lau HSH, Ho WK, Wong FY, Yang Q, Tan KW, Tan MH, Chay WY, Chia KS, Hartman M, Li J: Incidence of breast cancer attributable to breast density, modifiable and non-modifiable breast cancer risk factors in Singapore. Sci Rep. 2020, 10 (1): 503.

Barnard ME, Boeke CE, Tamimi RM: Established breast cancer risk factors and risk of intrinsic tumor subtypes. Biochim Biophys Acta. 2015, 1856 (1): 73-85.

Hines LM, Risendal B, Slattery ML, Baumgartner KB, Giuliano AR, Sweeney C, Rollison DE, Byers T: Comparative analysis of breast cancer risk factors among Hispanic and non-Hispanic white women. Cancer. 2010, 116 (13): 3215-23.

Rosner B, Glynn RJ, Eliassen AH, Hankinson SE, Tamimi RM, Chen WY, Holmes MD, Mu Y, Peng C, Colditz GA, Willett WC, Tworoger SS: A Multi-State Survival Model for Time to Breast Cancer Mortality among a Cohort of Initially Disease-Free Women. Cancer Epidemiol Biomarkers Prev. 2022, 31 (8): 1582-1592.

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What are the risk factors for breast cancer?

There are several risk factors for breast cancer, some of which are modifiable and others that are not.

Here are some of the most common risk factors:

1. Age: The risk of developing breast cancer increases with age, with most cases occurring in women over the age of 50.

2. Family history: Having a close relative, such as a mother, sister, or daughter, with breast cancer increases your risk.

3. Genetic mutations: Certain inherited gene mutations, such as BRCA1 and BRCA2, increase the risk of developing breast cancer.

4. Reproductive history: Early menarche (start of menstruation), late menopause, and having no children or having the first child after age 30 can increase the risk.

5. Hormone replacement therapy: Long-term use of combined estrogen and progesterone hormone therapy after menopause can increase the risk.

6. Alcohol consumption: Drinking alcohol increases the risk of breast cancer.

7. Obesity: Being overweight or obese increases the risk, especially after menopause.

8. Physical activity: Lack of physical activity can increase the risk.

9. Radiation exposure: Exposure to high doses of radiation, particularly during childhood, can increase the risk.

10. Breast density: Women with dense breasts have a higher risk of developing breast cancer.

11. Menstrual history: Women who started menstruating early (before age 12) or went through menopause late (after age 55) have a slightly higher risk.

12. Breastfeeding: Women who have never breastfed have a slightly higher risk of developing breast cancer.

It is important to note that having one or more risk factors does not mean that a person will definitely develop breast cancer, and not having any risk factors does not guarantee that a person will not develop breast cancer.

However, understanding these risk factors can help individuals make informed decisions about their health and potentially reduce their risk.

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