kanker usus besar, jua dikenal sebagai kanker kolorektal, disebabkan oleh pertumbuhan sel abnormal nang kada terkontrol di usus besar atau rektum.
penyebab pasti kanker usus besar kada diketahui, tapi beberapa faktor kawa meningkatkan resiko mengidap penyakit ini.
Nang ini tamasuk:
1. Umur: Risiko kanker usus besar meningkat seiring bertambahnya usia, dengan sebagian besar kasus terjadi pada orang di atas usia 50 tahun.
2. Riwayat keluarga: Riwayat pribadi atau keluarga kanker usus besar atau polip meningkatkan risiko terkena penyakit.
3. Sindrom bawaan: Sindrom genetik bawaan tertentu, nang kaya familial adenomatous polyposis (FAP) wan hereditary non-polyposis colorectal cancer (HNPCC), kawa maningkatakan risiko kanker usus besar.
4. Faktor gaya hidup: Diet tinggi daging merah dan olahan, obesitas, merokok, dan konsumsi alkohol berlebihan dapat meningkatkan risiko kanker usus besar.
5. Penyakit radang usus: Penyakit radang usus nang lawas, kaya kolitis ulseratif wan penyakit Crohn, kawa maningkatakan risiko kanker usus besar.
6. Diabetes tipe 2: Orang nang menderita diabetes tipe 2 lebih berisiko terkena kanker usus besar.
7. Terapi radiasi: Terapi radiasi gasan kanker lain di perut kawa maningkatakan risiko kanker usus besar.
8. Ras: Afrika Amerika lebih berisiko terkena kanker usus besar daripada ras lainnya.
Penting gasan dicatat bahwa baisi satu atawa labih faktor risiko ini kada harus baarti seseorang akan mengidap kanker usus besar, wan beberapa urang nang mengidap kanker usus besar mungkin kada baisi faktor risiko nang diketahui.
Pemeriksaan rutin wan deteksi dini kawa membantu mencegah kanker usus besar atawa mendeteksi tahap awal pas paling mudah diobati.
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Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.
Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.
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What causes colon cancer?
Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.
The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.
These include:
1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.
2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.
3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.
4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.
5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.
6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.
7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.
8. Race: African Americans have a higher risk of developing colon cancer than other races.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.
Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.
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