What causes Breast cancer?

Zerk sortzen du bularreko minbizia?

Ez dago bularreko minbiziaren kausa bakar bat, baina hainbat faktorek areagotu dezakete gaixotasuna garatzeko arriskua.

Faktore horietako batzuk honako hauek dira:

1. Adina: Bularreko minbizia izateko arriskua handitzen da emakumeak zahartzen doan heinean.

2. Familiako historia: Emakume baten bularreko minbizia izateko arriskua handiagoa da senide hurbil bat (ama, arreba edo alaba) bularreko minbizia izan badu.

3. Mutazio genetikoak: herentziazko mutazio batzuek, hala nola BRCA1 eta BRCA2, bularreko minbizia izateko arriskua handitzen dute.

4. Ugalketa-historia: Menstruazio goiztiarra, menopausi berantiarra, eta seme-alabarik ez izatea edo 30 urtetik aurrera lehen umea izatea bularreko minbiziaren arriskua handitu dezake.

5. Hormonaren ordezko terapia: Menopausarako hormonaren ordezko terapia hartzen duten emakumeek bularreko minbizia izateko arrisku handiagoa dute.

6. Alkohol-kontsumoa: Alkohol-kontsumoak bularreko minbizia izateko arriskua handitzen du.

7. Obesitatea: Gehiegizko pisua izateak edo obesitateak bularreko minbizia izateko arriskua handitzen du.

8. Jarduera fisikoa ez egitea: bizimodu sedentarioak bularreko minbizia izateko arriskua handitu dezake.

9. Erradiazio-exposizioa: Erradiazio-dosi altuen esposizioak, batez ere haurtzaroan, bularreko minbiziaren arriskua handitu dezake.

10. Bularreko dentsitatea: Bularreko dentsitatea duten emakumeek bularreko minbizia izateko arrisku handiagoa dute.

11. Menstruazio-historia: Menstruazioa goiz hasi edo menopausia berandu igaro duten emakumeek bularreko minbizia izateko arrisku apur bat handiagoa dute.

12. Bularra ematea: inoiz bularra eman ez duten emakumeek bularreko minbizia izateko arriskua apur bat handiagoa dute.

13. Jaiotza-kontrola: Oral kontraseptiboak erabiltzen dituzten emakumeek bularreko minbizia izateko arrisku apur bat handiagoa dute.

Garrantzitsua da kontuan hartzea arrisku-faktore horietako bat edo gehiago izateak ez duela esan nahi emakume batek bularreko minbizia garatuko duenik, eta bularreko minbizia garatzen duten emakume askok ez dute arrisku-faktore ezagunik.

Gainera, arrisku-faktore batzuk, hala nola adina eta familia-historia, ezin dira aldatu, beste batzuk, hala nola bizimodu-faktoreak, arriskua murrizteko aldatu daitezke.

Erreferentziak

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Yoneda T: Cellular and molecular basis of preferential metastasis of breast cancer to bone. J Orthop Sci. 2000, 5 (1): 75-81.

Demirci S, Eser E, Ozsaran Z, Tankisi D, Aras AB, Ozaydemir G, Anacak Y: Validation of the Turkish versions of EORTC QLQ-C30 and BR23 modules in breast cancer patients. Asian Pac J Cancer Prev. 2011, 12 (5): 1283-7.

Kluttig A, Schmidt-Pokrzywniak A: Established and Suspected Risk Factors in Breast Cancer Aetiology. Breast Care (Basel). , 4 (2): 82-87.

Tabar L, Duffy SW, Yen MF, Warwick J, Vitak B, Chen HH, Smith RA: All-cause mortality among breast cancer patients in a screening trial: support for breast cancer mortality as an end point. J Med Screen. 2002, 9 (4): 159-62.

Gonzalez P, Lim JW, Wang-Letzkus M, Flores KF, Allen KM, Castañeda SF, Talavera GA: Breast Cancer Cause Beliefs: Chinese, Korean, and Mexican American Breast Cancer Survivors. West J Nurs Res. 2015, 37 (8): 1081-99.

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What causes breast cancer?

There is no single cause of breast cancer, but several factors can increase the risk of developing the disease.

Some of these factors include:

1. Age: The risk of breast cancer increases as a woman gets older.

2. Family history: A woman's risk of breast cancer is higher if she has a close relative (mother, sister, or daughter) who has had breast cancer.

3. Genetic mutations: Certain inherited gene mutations, such as BRCA1 and BRCA2, increase the risk of breast cancer.

4. Reproductive history: Early menstruation, late menopause, and having no children or having the first child after age 30 can increase the risk of breast cancer.

5. Hormone replacement therapy: Women who take hormone replacement therapy for menopause have a higher risk of breast cancer.

6. Alcohol consumption: Drinking alcohol increases the risk of breast cancer.

7. Obesity: Being overweight or obese increases the risk of breast cancer.

8. Physical inactivity: A sedentary lifestyle can increase the risk of breast cancer.

9. Radiation exposure: Exposure to high doses of radiation, particularly during childhood, can increase the risk of breast cancer.

10. Breast density: Women with dense breasts have a higher risk of breast cancer.

11. Menstrual history: Women who started menstruating early or went through menopause late have a slightly higher risk of breast cancer.

12. Breastfeeding: Women who have never breastfed have a slightly higher risk of breast cancer.

13. Birth control: Women who use oral contraceptives have a slightly higher risk of breast cancer.

It is important to note that having one or more of these risk factors does not mean that a woman will definitely develop breast cancer, and many women who develop breast cancer have no known risk factors.

Additionally, some risk factors, such as age and family history, cannot be changed, while others, such as lifestyle factors, can be modified to reduce the risk.

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