Il- kanċer tal- kolon, magħruf ukoll bħala kanċer kolorettali, huwa kkawżat mit- tkabbir mhux ikkontrollat taʼ ċelloli anormali fil- kolon jew ir- rektum.
Il- kawża eżatta tal- kanċer tal- kolon mhix magħrufa, imma diversi fatturi jistgħu jżidu r- riskju li tiżviluppa l- marda.
Dawn jinkludu:
1. L- età: Ir- riskju taʼ kanċer tal- kolon jiżdied mal- età, u l- biċċa l- kbira mill- każijiet iseħħu f'nies li għandhom iktar minn 50 sena.
2. L- istorja tal- familja: L- istorja personali jew tal- familja taʼ kanċer tal- kolon jew polipi żżid ir- riskju li tiżviluppa l- marda.
3. Sindromi ereditarji: Ċerti sindromi ġenetiċi ereditarji, bħall- poliposi adenomatosa familjari (FAP) u l- kanċer kolorettali ereditarju mingħajr poliposi (HNPCC), jistgħu jżidu r- riskju ta ' kanċer tal- kolon.
4. Fatturi taʼ l- istil taʼ ħajja: Dieta b'ħafna laħam aħmar u pproċessat, l- obesità, it- tipjip, u l- konsum eċċessiv taʼ alkoħol jistgħu jżidu r- riskju taʼ kanċer tal- kolon.
5. Mard infjammatorju tal- intestini: Mard infjammatorju fit- tul tal- intestini, bħal kolite ulcerattiva u l- marda taʼ Crohn, jistaʼ jżid ir- riskju taʼ kanċer tal- kolon.
6. Dijabete tat- tip 2: In- nies bid- dijabete tat- tip 2 għandhom riskju akbar li jiżviluppaw kanċer tal- kolon.
8. Ir- razza: L- Afro-Amerikani għandhom riskju ogħla li jiżviluppaw kanċer tal- kolon milli razzi oħra.
Huwa importanti li wieħed jinnota li li jkollok wieħed jew aktar minn dawn il- fatturi ta ' riskju ma jfissirx neċessarjament li persuna se tiżviluppa kanċer tal- kolon, u xi nies li jiżviluppaw kanċer tal- kolon jistgħu ma jkollhom l- ebda fatturi ta ' riskju magħrufa.
Screening regolari u skoperta bikrija jistgħu jgħinu biex jipprevjenu l- kanċer tal- kolon jew jiskopruh fi stadju bikri meta jkun l- iktar li jistaʼ jiġi kkurat.
McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.
Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.
Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.
Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.
Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.
Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.
Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.
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Id-DMCA teħtieġ li n-notifika tiegħek ta' ksur allegat tad-drittijiet tal-awtur tinkludi l-informazzjoni li ġejja: (1) deskrizzjoni tax-xogħol protett bid-drittijiet tal-awtur li huwa s-suġġett ta' ksur allegat; (2) deskrizzjoni tal-kontenut allegatament li jikser id-drittijiet tal-awtur u informazzjoni suffiċjenti biex inkunu nistgħu nsibu l-kontenut; (3) informazzjoni ta' kuntatt għalik, inkluż l-indirizz tiegħek, in-numru tat-telefon u l-indirizz tal-email; (4) dikjarazzjoni minnek li għandek twemmin ta' fidi tajba li l-kontenut bil-mod li dwaru l-ilment ġie ppreżentat mhuwiex awtorizzat mid-detentur tad-drittijiet tal-awtur, jew mill-aġent tiegħu, jew mill-operazzjoni ta' kwalunkwe liġi;
(5) stqarrija minnek, iffirmata taħt il-piena ta' perjuri, li l-informazzjoni fin-notifika hija preċiża u li għandek l-awtorità li tinforza d-drittijiet tal-awtur li huma ddikjarati li ġew miksura;
u (6) firma fiżika jew elettronika tas-sid tad-drittijiet tal-awtur jew ta' persuna awtorizzata li taġixxi f'isem is-sid tad-drittijiet tal-awtur.
In-nuqqas li tinkludi l-informazzjoni kollha ta' hawn fuq jista' jwassal għal dewmien fit-trattament tal-ilment tiegħek.
Kuntatt
Jekk jogħġbok ibgħatilna email b'kull mistoqsija / suġġeriment.
What causes colon cancer?
Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.
The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.
These include:
1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.
2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.
3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.
4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.
5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.
6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.
7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.
8. Race: African Americans have a higher risk of developing colon cancer than other races.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.
Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.
Disclaimer: medical
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