How is Alzheimer diagnosed?

听这个页面 ⁇

阿尔茨海默症是怎么诊断的?

阿尔茨海默病是通过多种方法诊断的,包括彻底的医学评估,认知和神经心理测试,脑成像,以及消除其他可能原因的过程.

1. 医疗评估:医生会进行体检,并详细记录病史,以排除其他可能导致记忆力丧失或认知能力下降的原因,如甲状腺问题,维生素缺乏或脑肿瘤.

2. 认知和神经心理测试:这些测试评估记忆,语言,解决问题和其他认知功能,以确定认知障碍的程度,并区分正常与年龄相关的记忆丧失和痴呆症.

3. 脑成像:磁共振成像 (MRI) 或计算机断层扫描 (CT) 可以帮助识别可能表明阿尔茨海默病的大脑结构变化.

还可以使用正电子发射断层扫描 (PET) 来测量与阿尔茨海默病相关的某些蛋白质的水平.

4. 血液检查:最近的研究表明,某些血液检查可以通过测量与该疾病相关的特定蛋白质或生物标志物的水平来帮助诊断阿尔茨海默病.

5. 排除过程:由于阿尔茨海默病没有单一的明确测试,诊断通常涉及排除其他可能导致痴呆症症状的原因.

值得注意的是,阿尔茨海默病的确切诊断只能在死亡后通过检查脑组织进行.

然而,当前的诊断方法可以在人还活着时为临床诊断提供高水平的确定性.

早期诊断对于开始治疗和规划未来很重要.

参考资料

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.

Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.

Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.

[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.

Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

免责声明:医疗

本网站仅用于教育和信息目的,不构成提供医疗建议或专业服务.

提供的信息不应用于诊断或治疗健康问题或疾病, 寻求个人医疗建议的人应咨询有执照的医生.

请注意 , 产生答案的神经网络在数字内容方面是特别不准确的 , 比如 , 诊断出特定疾病的人数 ⁇

如果您认为您可能有医疗紧急情况,请立即拨打911或前往最近的急诊室. 本网站或其使用不会产生医生和患者的关系. BioMedLib或其员工,或本网站的任何贡献者,都不会对本网站提供的信息或其使用做出任何明确或暗示的声明.

免责声明:版权

1998年的"数字千年版权法" (Digital Millennium Copyright Act) 17 U.S.C. § 512 (DMCA) 为认为互联网上出现的材料侵犯了美国版权法规定的权利的版权所有者提供了补救.

如果您真诚地认为与我们的网站或服务有关的任何内容或材料侵犯了您的版权,您(或您的代理人)可以向我们发送通知,要求删除内容或材料,或阻止访问.

通知必须以书面形式通过电子邮件发送(请参阅"联系"部分以获取电子邮件地址).

DMCA 要求您的版权侵权通知包括以下信息: (1) 描述被指控侵权的受版权保护的作品; (2) 描述被指控侵权的内容和足够的信息,使我们能够找到内容; (3) 您的联系信息,包括您的地址,电话号码和电子邮件地址; (4) 声明您有诚信的信念,认为所投诉的方式的内容未经版权所有者或其代理人或任何法律的授权;

(5) 您签署的声明,以免作伪证,证明通知中的信息是准确的,并且您有权强制执行据称被侵犯的版权;

(6) 版权所有者或授权代表版权所有者行事的人员的实物或电子签名 ⁇

如果不包括上述所有信息,可能会导致投诉处理的延迟.

联系人

请向我们发送任何问题/建议的电子邮件.

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

Disclaimer: medical

This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.

The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.

Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.

Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.

Disclaimer: copyright

The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.